Patents Assigned to Oxford Genetics
  • Inducible AAV system comprising cumate operator sequences
    Patent number: 12410443
    Abstract: The invention relates to nucleic acid molecules, vectors and plasmids comprising AAV cap genes and rep genes, wherein the cap and rep genes are both operably-associated with an inducible promoter which comprises one or more cumate operator (CuO) sequences. The invention further relates to producer and packaging cell lines which are useful in the production of Adeno-Associated Virus (AAV) particles.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: September 9, 2025
    Assignee: Oxford Genetics
    Inventors: Ryan Cawood, Tom Payne, Alissa Bray