Abstract: Methods and systems for identification of microorganisms either after isolation from a culture or directly from a sample. The methods and systems are configured to identify microorganisms based on the characterization of proteins of the microorganisms via high-resolution/mass accuracy single-stage (MS) or multi-stage (MSn) mass spectrometry. Included herein are also discussion of targeted detection and evaluation of virulence factors, antibiotic resistance markers, antibiotic susceptibility markers, typing, or other characteristics using a method applicable to substantially all microorganisms and high-resolution/mass accuracy single-stage (MS) or multi-stage (MSn) mass spectrometry.
Type:
Grant
Filed:
May 22, 2015
Date of Patent:
December 18, 2018
Assignee:
OXIOD LIMITED
Inventors:
James L. Stephenson, Jr., Oksana Gvozdyak, Roger Grist, Clay Campbell, Iain C. Mylchreest, Ian D. Jardine