Patents Assigned to OXTOX LIMITED
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Patent number: 9011657Abstract: A device combining a fuel-cell-type breathalyzer with an electrochemical saliva drug test. The saliva drug tester comprises a disposable test strip-electrode module assembly and an analyzer module. The saliva is squeezed out of an absorbent swab when the test strip is inserted into the electrode module. The electrode module can also carry information that is read and evaluated by the analyzer, e.g. for verification of the electrode module.Type: GrantFiled: June 4, 2010Date of Patent: April 21, 2015Assignee: Oxtox LimitedInventors: John Parselle, Craig Banks, Peter Leslie James McMillan, Angelo Kotsis
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Patent number: 8877038Abstract: The invention provides an electrochemical assay for a phenol analyte in a body fluid sample wherein said sample, or fluid therefrom, is contacted with the working electrode of an electrode assembly comprising a working electrode, a counter-electrode, a voltage supply to said working and counter-electrodes and a current meter for determining the current between said working and counter-electrodes, and wherein a first compound capable of reversible oxidation and reduction is disposed at said working electrode, said first compound being capable in either an oxidized or a reduced form of binding to said phenol analyte, characterized in that said first compound in its oxidized or reduced form comprises a group of structure I R1-NH—C*—(C*—C*)n—C*-QR? (I) (where n is 0 or 1; Q is 0, S, NH or NR?; C*—(C*—C*)n—C* is a two or four carbon string in a conjugated delocalised electron system optionally substituted by a group comprising R; R is an electron-donating or withdrawing substituent; and R? is H or a group R, at leType: GrantFiled: April 24, 2009Date of Patent: November 4, 2014Assignee: Oxtox LimitedInventors: Dimitrios Konstantinos Kampouris, Rashid Olukayoee Kadara, Patrick Robinson Huddleston, Craig Edward Banks
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Patent number: 8785204Abstract: The invention provides a method of assaying for tetrahydrocannabinol in a body fluid. The method includes contacting a sample of body fluid with an imine capable of reacting with tetrahydrocannabinol to yield a quinone imine, and detecting the formation of a quinone imine, where the sample is contacted with the reagent compound at a pH of at least 10.5.Type: GrantFiled: January 28, 2010Date of Patent: July 22, 2014Assignee: Oxtox LimitedInventors: Dimitrios Konstantinos Kampouris, Patrick Robinson Huddleston, Craig Edward Banks
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Patent number: 8541239Abstract: The invention provides an assay method for the detection of a primary amine analyze in an aqueous body fluid, which method comprises contacting a sample of said body fluid at a pH below 9.5 with a thiol and an unsaturated cis-dialdehyde and testing for the presence of a pyrrole reaction product.Type: GrantFiled: October 15, 2009Date of Patent: September 24, 2013Assignee: Oxtox LimitedInventors: Dimitrios Konstantinos Kampouris, Patrick Robinson Huddleston, Craig Edward Banks
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Publication number: 20120132524Abstract: A device combining a fuel-cell-type breathalyser with an electrochemical saliva drug test. The saliva drug tester comprises a disposable test strip-electrode module assembly and an analyser module. The saliva is squeezed out of an absorbent swab when the test strip is inserted into the electrode module. The electrode module can also carry information that is read and evaluated by the analyser, e.g. for verification of the electrode module.Type: ApplicationFiled: June 4, 2010Publication date: May 31, 2012Applicant: OXTOX LIMITEDInventors: John Parselle, Craig Banks, Peter Leslie James McMillan, Angelo Kotsis
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Publication number: 20120122229Abstract: The invention provides a method of assaying for tetrahydrocannabinol in a body fluid, said method comprising contacting a sample of body fluid with an imine capable of reacting with tetrahydrocannabinol to yield a quinone imine, and detecting the formation of a quinone imine, characterised in that said sample is contacted with said reagent compound at a pH of at least 10.5.Type: ApplicationFiled: January 28, 2010Publication date: May 17, 2012Applicant: OXTOX LIMITEDInventors: Dimitrios Konstantinos Kampouris, Patrick Robinson Huddleston, Craig Edward Banks
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Publication number: 20110312100Abstract: The invention provides an assay method for the detection of a primary amine analyte in an aqueous body fluid, which method comprises contacting a sample of said body fluid at a pH below 9.5 with a thiol and an unsaturated cis-dialdehyde and testing for the presence of a pyrrole reaction product.Type: ApplicationFiled: October 15, 2009Publication date: December 22, 2011Applicant: OXTOX LIMITEDInventors: Dimitrios Konstantinos Kampouris, Patrick Robinson Huddleston, Craig Edward Banks
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Publication number: 20110168576Abstract: The invention provides an electrochemical assay for a phenol analyte in a body fluid sample wherein said sample, or fluid therefrom, is contacted with the working electrode of an electrode assembly comprising a working electrode, a counter-electrode, a voltage supply to said working and counter-electrodes and a current meter for determining the current between said working and counter-electrodes, and wherein a first compound capable of reversible oxidation and reduction is disposed at said working electrode, said first compound being capable in either an oxidized or a reduced form of binding to said phenol analyte, characterized in that said first compound in its oxidized or reduced form comprises a group of structure I R1-NH—C*—(C*—C*)n—C*-QR? (I) (where n is 0 or 1; Q is 0, S, NH or NR?; C*—(C*—C*)n—C* is a two or four carbon string in a conjugated delocalised electron system optionally substituted by a group comprising R; R is an electron-donating or withdrawing substituent; and R? is H or a group R, at leType: ApplicationFiled: April 24, 2009Publication date: July 14, 2011Applicant: OXTOX LIMITEDInventors: Dimitrios Konstantinos Kampouris, Rashid Olukayoee Kadara, Patrick Robinson Huddleston, Craig Edward Banks
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Publication number: 20110042241Abstract: A fluid assay system comprises a swab having an absorbent portion for receiving and retaining a fluid sample. The system also comprises an electrode module having at least one electrode, arranged so that it can be selectively placed over the absorbent portion of the swab in order to contact the electrode with the fluid sample. The system further comprises a reader module configured to process signals from the electrode module, with the electrode and reading modules arranged such that they can be coupled together for communication of the signals from the electrode module to the reader module.Type: ApplicationFiled: December 22, 2008Publication date: February 24, 2011Applicant: OXTOX LIMITEDInventors: Angelo Kotsis, John Brown, Claudia Bonifer, Peter McMillan, John Parselle