Abstract: Polymer filter film for which pores are etched along beam tracks only in a first, porous region (P1), and which has a second, impermeable region (R1), in particular in the form of a peripheral region. The peripheral region (R1) is made etch-resistant by a heat treatment of the beam tracks. Advantageous embodiments of the method are used to produce microchambers in the film for holding a cell culture. They can advantageously be used for enzymatic sensors and microbiological reactors.