Abstract: The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphospahte (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells.
Type:
Grant
Filed:
April 29, 2003
Date of Patent:
August 1, 2006
Assignee:
OxyPlus, Inc.
Inventors:
Yves Claude Nicolau, Jean-Marie Lehn, Konstantina Fylaktakidou, Ruth Greferath