Abstract: A method and apparatus to kill pathogens with ozone and singlet oxygen. Includes steps of providing a reaction chamber, establishing an elevated electrical force field in the reaction chamber and moving a gas containing normal oxygen (O.sub.2) through the chamber to permit ionization and consequent reaction within the gas which converts the oxygen (O.sub.2) into constituents of ozone (O.sub.3) and singlet oxygen (O.sub.1). Next moves gas containing constituents into contact with pathogens to kill pathogens. Invention is applied to sterilize medical instruments and containers, and when applied to human skin surfaces, for treatment of pathogenic infestations.