Abstract: Vaccines and methods are for immunization against Coxiella burnetii infections and Q fever. The vaccine can be for protection against a Coxiella burnetii infection, or treating or preventing at least one symptom of Q fever. The vaccine includes a delipidated C. burnetii polysaccharide derived from a cell wall lipopolysaccharide of C. burnetii. The vaccine can also be a conjugate vaccine for protection against a Coxiella burnetii infection, or treating or preventing at least one symptom of Q fever. The conjugate vaccine includes a delipidated C. burnetii polysaccharide derived from a cell wall lipopolysaccharide of C. burnetii linked to an immunogenic carrier.
Type:
Grant
Filed:
November 6, 2018
Date of Patent:
June 29, 2021
Assignee:
OZQ PTY LTD
Inventors:
Stephen Roger Graves, John Stenos, Moira Cecelia Graves, Rudolf Toman, Rodney Carbis