Patents Assigned to P. N. Gerolymatos S.A.
  • Use of phanquinone for the treatment of alzheimer's disease
    Patent number: 6670369
    Abstract: The use of phanquinone for the manufacture of a pharmaceutical composition for the prevention or the treatment of Alzheimer's disease is disclosed. Also methods of treatment or prevention of Alzheimer's disease are disclosed.
    Type: Grant
    Filed: October 19, 2000
    Date of Patent: December 30, 2003
    Assignee: P.N. Gerolymatos S.A.
    Inventors: Michel Xilinas, Panayotis Nikolas Gerolymatos
  • Pharmaceutical formulations comprising labdanes for the treatment of tumors or leukemias
    Patent number: 6652877
    Abstract: The present invention relates to novel compositions based on hydrated lipidic lamellar phases or liposomal compositions, prepared by combining different lipid molecules, synthetic and/or from natural sources, said compositions comprising at least one of a) labd-13-ene-8&agr;, 15-diol and/or derivatives thereof; b) labd-14-ene-8, 13-diol or derivatives thereof; c) 3&bgr;-hydroxy-labd-14-ene-8, 13-epoxy and/or derivatives thereof, d) a plant extract containing the aforementioned labdenes or derivatives thereof. The compositions of the invention exhibit cytotoxicity against cancerous cells and are utilized for the treatment of tumors and leukemias.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: November 25, 2003
    Assignee: P.N. Gerolymatos S.A.
    Inventors: Thalia Anastassaki, Demetra Angelopoulou, Demetrios Kokkinopoulos, Constantinos Dimas, Constantinos Demetzos
  • Ionic aqueous composition containing levomenthol
    Patent number: 6548554
    Abstract: A composition for relieving a sensation of respiratory discomfort and/or for promoting natural regeneration of mucous membranes of the nasal cavity. The composition contains levomenthol at a concentration between 10 and 250 mg/l, dissolved in an aqueous ionic solution having an osmolarity at least equal to that of an aqueous solution of sodium chloride at 9 g/l. The aqueous ionic solution is pure sea water, diluted sea water, an aqueous sodium chloride solution, an aqueous sodium chloride solution further containing at least one salt found in sea water, or a mixture thereof.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: April 15, 2003
    Assignee: P. N. Gerolymatos S.A.
    Inventor: Yves Théodore Tillet
  • Use of phanquinone for the treatment or prevention of memory impairment
    Publication number: 20030055078
    Abstract: The use of phanquinone (4,7-phenanthroline-5,6-dione) for the treatment or prevention of memory impairment is suggested. Also a method for improving the learning or memory of a normal subject is suggested, said method comprising the administering of phanquinone, optionally together with one or more pharmaceutically acceptable carrier(s).
    Type: Application
    Filed: March 15, 2002
    Publication date: March 20, 2003
    Applicant: P. N. Gerolymatos S.A.
    Inventors: Michel Xilinas, Panayotis Nikolas Gerolymatos
  • Clioquinol for the treatment of Alzheimer's disease
    Patent number: 6001852
    Abstract: A new pharmaceutical composition is disclosed that comprises clioquinol, vitamin B.sub.12, and, optionally, pharmaceutical acceptable carriers and/or excipients. The use of the pharmaceutical composition removes or alleviates the side effects of clioquinol.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: December 14, 1999
    Assignee: P.N. Gerolymatos S.A.
    Inventor: Panayotis N. Gerolymatos
  • Pharmaceutical compositions comprising clioquinol in combination with vitamin B12 and therapeutic and prophylactic uses thereof
    Patent number: 5994323
    Abstract: A pharmaceutical composition is disclosed that comprises clioquinol, vitamin B.sub.12, and, optionally, pharmaceutical acceptable carriers and/or excipients. The use of the pharmaceutical composition removes or alleviates the side effects of clioquinol.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: November 30, 1999
    Assignee: P.N. Gerolymatos S.A.
    Inventor: Panayotis N. Gerolymatos
  • Clioquinol for the treatment of Parkinson's disease
    Patent number: 5980914
    Abstract: A new pharmaceutical composition is disclosed that comprises clioquinol, vitamin B.sub.12, and, optionally, pharmaceutical acceptable carriers and/or excipients. The use of the pharmaceutical composition removes or alleviates the side effects of clioquinol.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: November 9, 1999
    Assignee: P.N. Gerolymatos S.A.
    Inventor: Panayotis N. Gerolymatos