Patents Assigned to PAIRWISE PLANTS SERVICES, INC.
  • Mutation of growth regulating factor family transcription factors for enhanced plant growth
    Patent number: 11965170
    Abstract: This invention relates to compositions and methods for modifying Growth Regulating Factor (GRF) family transcription factors in plants to produce plants having improved phenotypic characteristics including increased growth. The invention further relates to plants produced using the methods and compositions of the invention.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: April 23, 2024
    Assignee: Pairwise Plants Services, Inc.
    Inventor: Brian Charles Wilding Crawford
  • Suppression of shade avoidance response in plants
    Patent number: 11959072
    Abstract: This invention relates to compositions and methods for modifying Homeodomain-leucine zipper (HD-Zip) transcription factors in plants to suppress shade avoidance response in plants. The invention further relates to plants produced using the methods and compositions of the invention.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: April 16, 2024
    Assignee: Pairwise Plants Services, Inc.
    Inventors: Nicholas Bate, Yongjoo Kim, Nathaniel Graham, Julius Mojica
  • Compositions and methods for RNA-encoded DNA-replacement of alleles
    Patent number: 11926834
    Abstract: This invention relates to recombinant nucleic constructs comprising Type V CRISPR-Cas effector proteins, reverse transcriptases and extended guide nucleic acids and methods of use thereof for modifying nucleic acids in plants.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: March 12, 2024
    Assignee: Pairwise Plants Services, Inc.
    Inventors: Joseph Matthew Watts, Aaron Hummel, Yongjoo Kim, Shai Joshua Lawit, David Schwark
  • Optimized CRISPR-Cas nucleases and base editors and methods of use thereof
    Patent number: 11913005
    Abstract: This invention relates to CRISPR-Cas nucleases codon optimized for expression in plants and nucleic acid constructs encoding base editors comprising a CRISPR-Cas nuclease and a deaminase domain, wherein the nucleic acid constructs are optimized for expression in a plant. The invention further relates to methods of modifying nucleic acids using the nucleic acid constructs.
    Type: Grant
    Filed: October 20, 2022
    Date of Patent: February 27, 2024
    Assignee: Pairwise Plants Services, Inc.
    Inventor: Nathaniel Graham
  • Methods for improving resistance to soybean rust
    Patent number: 11882808
    Abstract: This invention relates to compositions and methods for modifying STAYGREEN (SGR) genes in plants. The invention further relates to plants produced using the methods and compositions of the invention comprising modified endogenous SGR genes and having increased resistance to soybean rust.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: January 30, 2024
    Assignee: Pairwise Plants Services, Inc.
    Inventor: Marisa Miller
  • Variants of CAS12A nucleases and methods of making and use thereof
    Patent number: 11866745
    Abstract: This invention relates to variants of Cas12a nucleases having altered protospacer adjacent motif recognition specificity. The invention further relates to methods of making CRISPR-CAS nuclease variants and methods of modifying nucleic acids using the variants.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: January 9, 2024
    Assignee: Pairwise Plants Services, Inc.
    Inventor: Joseph Matthew Watts
  • Optimized protein linkers and methods of use
    Patent number: 11718838
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based adenine base editors.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: August 8, 2023
    Assignee: Pairwise Plants Services. Inc.
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • Optimized protein linkers and methods of use
    Patent number: 11708568
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based cytosine base editors.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: July 25, 2023
    Assignee: Pairwise Plants Services, Inc.
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • Optimized CRISPR-Cas nucleases and base editors and methods of use thereof
    Patent number: 11591607
    Abstract: This invention relates to CRISPR-Cas nucleases codon optimized for expression in plants and nucleic acid constructs encoding base editors comprising a CRISPR-Cas nuclease and a deaminase domain, wherein the nucleic acid constructs are optimized for expression in a plant. The invention further relates to methods of modifying nucleic acids using the nucleic acid constructs.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: February 28, 2023
    Assignee: Pairwise Plants Services, Inc.
    Inventors: Nathaniel Graham, Aaron Hummel, Yongjoo Kim, Joseph Matthew Watts
  • Optimized protein linkers and methods of use
    Patent number: 11072785
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based cytosine base editors.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: July 27, 2021
    Assignee: PAIRWISE PLANTS SERVICES, INC.
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts