Abstract: The specification discloses a cardboard and blister pack packaging and sealing machine that includes an upper and lower heater and die combination that can be compressed together over a package for sealing using heat activated adhesives. The machine may use at least one piston and rod device or pump to provide the necessary energy or pressure. The machine may include a moveable tray containing at least one aperture to hold an unsealed package wherein the unsealed package can be moved proximate to the upper and lower heaters and dies and the upper and lower heaters and dies can press together. In this way, both the top and bottom dies may be heated and the operator is not required to remove the sealed packaging from the hot die.