Patents Assigned to Palau Pharma, S.A.
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Patent number: 8536194Abstract: New compounds of formula (I) and the salts thereof, wherein the meanings for the various substituents are as disclosed in the description, are useful as p38 kinase inhibitors.Type: GrantFiled: September 8, 2008Date of Patent: September 17, 2013Assignee: Palau Pharma, S.A.Inventors: Carmen Almansa Rosales, Marina Virgili Bernadó
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Patent number: 8501735Abstract: N-containing heteroaryl derivatives of formula I or II, wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as JAK, particularly JAK3, kinase inhibitors.Type: GrantFiled: October 29, 2010Date of Patent: August 6, 2013Assignee: Palau Pharma, S.A.Inventors: Carmen Almansa Rosales, Jorge Salas Solana, Robert Soliva Soliva, Sergio Rodriguez Escrich, Maria Cristina Sicre González
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Patent number: 8476456Abstract: Process for the preparation of 4-(imidazol-1-yl)benzenesulfonamide derivatives of formula I, wherein R1 represents optionally substituted aryl or heteroaryl, which comprises treating a compound of formula II, wherein R1 has the same meaning defined in the formula I and But represents tert-butyl, with an acid. The 4-(imidazol-1-yl)benzenesulfonamide derivatives of formula I are useful as anti-inflammatory agents.Type: GrantFiled: April 1, 2008Date of Patent: July 2, 2013Assignee: Palau Pharma, S.A.Inventors: Carmen Almansa Rosales, Concepción González González
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Patent number: 8431580Abstract: 4-Aminopyrimidine derivatives of formula (I) that are useful as histamine H4 receptor antagonists.Type: GrantFiled: December 18, 2008Date of Patent: April 30, 2013Assignee: Palau Pharma, S.A.Inventors: Elena Carceller González, Eva Maria Medina Fuentes, Robert Soliva Soliva, Marina Virgili Bernadó, Josep Martí Via
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Patent number: 8309105Abstract: New triflusal-containing polymeric compounds resulting from the polymerization of 2-(methacryloyloxy)ethyl 2-acetyloxy-4-(trifluoromethyl)benzoate with butyl acrylate are described. These new polymers exhibit good adhesion and crack-bridging properties and are particularly suitable for the coating of stents.Type: GrantFiled: September 20, 2006Date of Patent: November 13, 2012Assignee: Palau Pharma, S.A.Inventors: Julio San-Román Del Barrio, Gema Rodríguez Crespo, Mar Fernández Gutiérrez, Alberto Gallardo Ruiz, Luis Duocastella Codina, Maria Molina Crisol
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Patent number: 8258296Abstract: The present subject matter relates to novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one represented by Formula II: , pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV V, and VI of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one.Type: GrantFiled: December 16, 2010Date of Patent: September 4, 2012Assignee: Palau Pharma, S.A.Inventors: Antonio Cánovas Paredes, Javier Bartroli Orpi, Elies Molins Grau, Anna Roig Serra, Kevin Meyer, Keith Lorimer
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Publication number: 20120128612Abstract: The present invention relates generally to antifugal compositions. In an embodiment, the antifungal compositions are effective for application to nails and surrounding skin, and comprise at least one volatile solvent, at least one film forming substance, and at least one pyrimidone derivative of formula I, such as albaconazole. These compositions are capable of treating an infection caused by fungi, such as onychomychosis.Type: ApplicationFiled: May 27, 2010Publication date: May 24, 2012Applicant: PALAU PHARMA, S.A.Inventors: Jon Lenn, Hans Hofland, Edward Hsia
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Publication number: 20110092702Abstract: Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV, V, and VI of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one.Type: ApplicationFiled: December 16, 2010Publication date: April 21, 2011Applicants: PALAU PHARMA, S.A., STIEFEL LABORATORIES, INC.Inventors: Antonio Cánovas PAREDES, Javier Bartroli ORPI, Elies Molins GRAU, Anna Roig SERRA, Kevin MEYER, Keith LORIMER
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Patent number: 7879867Abstract: Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2 -hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms.Type: GrantFiled: August 6, 2007Date of Patent: February 1, 2011Assignees: Palau Pharma, S.A., Stiefel Laboratories, Inc.Inventors: Antonio Cánovas Paredes, Javier Bartroli Orpi, Elies Molins Grau, Anna Roig Serra, Kevin Meyer, Keith Lorimer
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Publication number: 20100222363Abstract: New bicyclic derivatives of formula (I); wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.Type: ApplicationFiled: June 28, 2006Publication date: September 2, 2010Applicant: PALAU PHARMA, S.A.Inventors: Carmen Almansa Rosales, Marina Virgili Bernadó
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Publication number: 20090286775Abstract: New bicyclic derivatives of formula (I), wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.Type: ApplicationFiled: June 28, 2006Publication date: November 19, 2009Applicant: PALAU PHARMA, S.A.Inventors: Carmen Almansa Rosales, Marina Virgili Bernadó
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Publication number: 20090286983Abstract: New compounds of formula (I) and the salts thereof, wherein the meanings for the various substituents are as disclosed in the description, are useful as p38 kinase inhibitors.Type: ApplicationFiled: July 29, 2009Publication date: November 19, 2009Applicant: PALAU PHARMA, S.A.Inventors: Carmen Almansa Rosales, Marina Virgili Bernadó
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Publication number: 20090264446Abstract: New compounds of formula (I), wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.Type: ApplicationFiled: August 2, 2005Publication date: October 22, 2009Applicant: Palau Pharma, S.A.Inventors: Carmen Almansa Rosales, Marina Virgili Bernado, Pedro Manuel Grima Poveda
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Patent number: 7589125Abstract: The present invention relates to novel compounds of formula (I) and to the salts, solvates and prodrugs thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful for the treatment or prevention of psoriasis and other immune diseases.Type: GrantFiled: July 17, 2003Date of Patent: September 15, 2009Assignee: Palau Pharma, S.A.Inventors: Javier Bartrolí Orpí, Carmen Almansa Rosales, Alberto Fernández De Arriba
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Patent number: 7550497Abstract: New phosphoramide derivatives of formula (I) and the salts and solvates thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful as antiinflammatory and analgesic agents.Type: GrantFiled: December 23, 2003Date of Patent: June 23, 2009Assignee: Palau Pharma, S.A.Inventors: Carmen Almansa Rosales, Javier Bartroli Orpi
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Publication number: 20090012307Abstract: Process for the preparation of 4-(imidazol-1-yl)benzenesulfonamide derivatives of formula I, wherein R1 represents optionally substituted aryl or heteroaryl, which comprises treating a compound of formula II, wherein R1 has the same meaning defined in the formula I and But represents tert-butyl, with an acid. The 4-(imidazol-1-yl)benzenesulfonamide derivatives of formula I are useful as anti-inflammatory agents.Type: ApplicationFiled: April 1, 2008Publication date: January 8, 2009Applicant: PALAU PHARMA, S.A.Inventors: Carmen Almansa Rosales, Concepcion Gonzalez Gonzalez
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Publication number: 20090005377Abstract: New compounds of formula (I) and the salts thereof, wherein the meanings for the various substituents are as disclosed in the description, are useful as p38 kinase inhibitors.Type: ApplicationFiled: September 8, 2008Publication date: January 1, 2009Applicant: PALAU PHARMA, S.A.Inventors: Carmen Almansa Rosales, Marina Virgili Bernado
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Publication number: 20080318977Abstract: New compounds of formula (I), wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.Type: ApplicationFiled: August 2, 2005Publication date: December 25, 2008Applicant: Palau Pharma, S.A.Inventors: Carmen Almansa Rosales, Marina Virgili Bernado, Pedro Manuel Grima Poveda
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Patent number: 7468376Abstract: New compounds of formula (I) and the salts, solvates and prodrugs thereof, wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.Type: GrantFiled: February 27, 2004Date of Patent: December 23, 2008Assignee: Palau Pharma, S.A.Inventors: Carmen Almansa Rosales, Marina Virgili Bernadó
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Patent number: 7445789Abstract: New biocompatible polymeric systems carrying triflusal or HTB are described which result from the polymerization of a monomer A of the acrylic or vinylic type and carrying triflusal or HTB, wherein triflusal or HTB are linked to the remainder of the molecule of said monomer through an in vivo hydrolysable covalent bond, and optionally a second polymerisable monomer B. These new polymeric systems are useful as coating for synthetic biomaterials.Type: GrantFiled: November 7, 2005Date of Patent: November 4, 2008Assignee: Palau Pharma, S.A.Inventors: Alberto Gallardo Ruiz, Gema Rodriguez Crespo, Julio San Román del Barrio