Abstract: An apparatus for processing cells is disclosed. In one embodiment, a fixed bed reactor is provided for the cells, the fixed bed reactor including a portion movable from a first position corresponding to a packed condition of the fixed bed to a second position corresponding to a depacked condition of the fixed bed. Movement of the partition facilitates harvesting of the cells there from. Related apparatus, kits, methods, and systems are also disclosed.
Type:
Grant
Filed:
December 11, 2013
Date of Patent:
September 22, 2020
Assignees:
PALL TECHNOLOGY UK LIMITED, PALL ARTELIS BVBA, PALL LIFE SCIENCES BELGIUM B.V.B.A.
Inventors:
Suresh Purushothaman, Jose Antonio Castillo Gonzalez, Jean-Christophe Drugmand, Vishwas Pethe, Derek Pendlebury, Fabien Moncaubeig
Abstract: An apparatus for processing cells is disclosed. In one embodiment, a fixed bed reactor is provided for the cells, the fixed bed reactor including a portion movable from a first position corresponding to a packed condition of the fixed bed to a second position corresponding to a depacked condition of the fixed bed. Movement of the partition facilitates harvesting of the cells there from. Related apparatus, kits, methods, and systems are also disclosed.
Type:
Application
Filed:
December 11, 2013
Publication date:
November 12, 2015
Applicants:
PALL TECHNOLOGY UK LIMITED, PALL LIFE SCIENCES BELGIUM, PALL ARTELIS BVBA
Inventors:
Suresh PURUSHOTHAMAN, Jose Antonio CASTILLO GONZALEZ, Jean-Christophe DRUGMAND, Vishwas PETHE, Derek PENDLEBURY, Fabien MONCAUBEIG
Abstract: The present invention relates to a cell culture device (1) comprising a disposable culture vessel comprising at least one external wall made of a material having a Young modulus E of less than 50 GPa, in which there is situated at least one cell culture zone and at least one cell-free medium transfer zone, allowing a flow of a culture medium between the cell culture zone and the transfer zone, and at least one sensor element of a cell-density sensor wherein said sensor element is situated in the cell culture zone of said vessel. The sensor element is an electrode arrangement of at least two and preferably at least four measuring electrodes arranged on the inner side of an external wall of the disposable culture vessel and directed towards the cell culture zone. The present invention further relates to a method of culturing cells.
Abstract: Mixing system comprising: a flexible bag (28) with a mixing device (1) comprising a magnetic impeller; and an alignment facilitation device adapted to facilitate alignment between the magnetic impeller and a magnetic driver (36) located external to the system. Specific flexible bag and hardware therefore.
Type:
Grant
Filed:
September 14, 2012
Date of Patent:
September 30, 2014
Assignee:
Pall Artelis BVBA
Inventors:
Jose Castillo, Florence Bosco, Samuel Osumba