Abstract: A connector assembly for fluid filter elements is provided comprising first and second connector elements each comprising at least two connector snap arches, each of the connector snap arches including a snap tooth lock; and at least two connector snap arms, each of the connector snap arms including a snap tooth; each connector element having a central opening, and an annular channel for receiving an end of a hollow cylindrical filter element; a gasket arranged between the first connector element and the second connector element, the gasket having a central opening; wherein the first connector element and the second connector element are lockably engageable with each other when placed in contact with each other and axial force is applied such that respective connector snap tooth is retained in each respective connector snap tooth.

Abstract: Methods and systems for recovering retained filtered fluid are provided.

Abstract: A valve assembly used in a manifold system fix processing fluid samples includes a body, a valve member, and a coupling assembly. The body defines a fluid passage and a valve passage in communication with the fluid passage and receiving at least a portion of the valve member therein. The valve member is selectively movable over a range of travel between an open position, in which fluid can flow through the fluid passage, and a closed position, in which the valve member occludes the fluid passage. The coupling assembly includes a coupling member and a retention lug. The retention lug is connected to one of the body and the coupling member. The other of the body and the coupling member defines a lug raceway configured to removably receive the retention lug therein to removably mount the coupling member to the body with the valve member being movably retained therebetween.

Abstract: Methods and systems for recovering retained filtered fluid are provided.

Abstract: An agitator comprising a rotatable impeller comprising blades, magnets, and a shaft, wherein the impeller is configured to be driven by a drive unit magnetically coupled to the impeller, and an impeller seat receiving the rotatable impeller, the impeller seat comprising an upwardly arranged cylindrical housing, a flange, and a base, the cylindrical housing comprising a central opening for the impeller shaft, and the base comprising a collar and pins arranged to engage with a locking and centering mechanism, as well as a mixer engagement unit including the agitator, a mixer system, a mixing vessel, and methods of using the agitator, mixer engagement unit, mixer system, and mixing vessel, are disclosed.

Abstract: A biocontainer assembly includes a biocontainer bag, a support frame, and a capacitive fill level sensor. The biocontainer bag defines a storage volume. The support frame includes a shelf having a support surface disposed at an oblique angle with respect to a horizontal axis. The capacitive fill level sensor is mounted to the support surface and is configured to generate a fill level signal indicative of the amount of material within the storage volume of the biocontainer bag.

Abstract: A buffer management system includes a supply of concentrated buffer solution, an inline dilution skid having a manifold in fluid communication with the supply of concentrated buffer solution and a control unit configured to operate the dilution skid to selectively dilute the supply of concentrated buffer solution in the manifold with a source of water for injection (WFI), and a biocontainer assembly. The biocontainer assembly includes a biocontainer bag defining a storage volume and a fill level sensor configured to generate a fill level signal indicative of the amount of material within the storage volume of the biocontainer bag. The biocontainer bag is in fluid communication with the manifold of the dilution skid for storing diluted buffer solution therein. The fill level sensor communicates the fill level signal to the control unit of the dilution skis, which uses it to manage the operation of the dilution skid.

Abstract: A buffer management system includes at least one workstation configured to support a supply of concentrated buffer solution and an inline dilution skid having a manifold. The manifold is in fluid communication with the supply of concentrated buffer solution and is adapted to be placed in fluid communication with a source of water for injection (WFI). The manifold includes a buffer inlet line in selective fluid communication with the supply of concentrated buffer solution, a WFI inlet line in selective fluid communication with the source of WFI, and a discharge line in fluid communication with both the buffer inlet line and the WFI inlet line. The inline dilution skid is configured to variably mix the supply of concentrated buffer solution and the source of WFI to obtain a range of diluted buffer solutions.

Abstract: A buffer management system includes at least one workstation configured to support a supply of concentrated buffer solution and an inline dilution skid having a manifold and at least one workstation to support delivery of diluted (surge) buffers from the inline dilution skid. The latter workstation also serves to supply ready-made (diluted) buffers to a bioprocessing unit. The manifold is in fluid communication with the supply of concentrated buffer solution and is adapted to be placed in fluid communication with a source of water for injection (WFI). The inline dilution skid is configured to variably mix the supply of concentrated buffer solution and the source of WFI to obtain a range of diluted buffer solutions. Processes for automatically identifying the arrangement of buffer solutions in a bioprocessing application use signals from various sensors to identify the fluid connections between components of the system.

Abstract: A manifold assembly and a method of engaging a filter capsule in the manifold assembly are provided.

Abstract: Disclosed is a porous medium, e.g., a bead, fiber, or membrane, comprising a porous support and a crosslinked polymer coating, wherein the polymer of the crosslinked polymer coating comprises at least one of polymerized monomer (A), at least one of polymerized monomer (B), at least one of polymerized monomer (C), wherein monomers (A)-(C) are as defined herein. Also disclosed are methods of preparing the porous medium and of treating a fluid containing a desired protein and one or more negatively charged species or of removing metals from organic solvents used in the microelectronics industry.

Abstract: Disclosed are porous membranes including a porous support and a coating comprising a copolymer having monomeric units A and B, and optionally monomeric units C; wherein A is a halogenated vinyl monomer other than tetrafluoroethylene, a halogenated alkyl vinyl ether, or an alkene of the formula CnH2n, wherein n is 1-6; B is a perfluoro (alkyl vinyl)ether compound, a perfluoroalkyl vinyl compound, or a perfluoro alkoxyalkyl vinyl ether compound, each compound having one or more sulfonic acid groups or a salt thereof, one or more sulfonyl fluoride groups, one or more sulfonamide groups, or one or more sulfonate ester groups, and C is vinylidene fluoride. Also disclosed are methods of preparing such porous membranes and methods of treating fluids by the use of these membranes.

Abstract: A manifold assembly including a linear guide and a method of engaging a filter capsule in the manifold assembly are provided.

Abstract: The invention proceeds from a filter device which is provided for stabilising a liquid, having at least one filter unit, a membrane filter unit, which has at least one filter element and at least one integrated stabiliser. It is proposed that the filter unit has at least one further integrated stabiliser. It is proposed in a further aspect of the invention that the filter device comprises at least one first precursor which is provided for forming the filter element at least partially, and the same first precursor is provided for forming the stabiliser at least partially.

Abstract: A water processing device is provided for removing micro-pollutants, in particular medicaments, from water, the device comprising at least one filter unit which is provided for at least one filtering of water in at least one operating state and which comprises at least one tubular filter element with at least two end portions, and comprising at least one adsorption unit which at least partially adsorbs the micro-pollutants in at least one operating state, wherein the at least two end portions enclose an inner angle of from 0° to 90° when in the assembled state.

Abstract: Support and drainage materials, each comprising an element comprising a section having a first end and a second end, and a first major surface, and a plurality of parallel tapered flow channels extending from the first end to the second end, the tapered flow channels comprising tapered side walls arranged in parallel and projecting upwardly from, and perpendicular to, the first major surface, the tapered flow channels having a deeper end and a shallower end, and being deeper at the first end of the section than at the second end of the section, wherein the tapered flow channels are connected at the first end with a cross member, and connected at the second end with a cross member, filters including the materials, and methods of use are disclosed.

Abstract: Disclosed are methods for determining and classifying aircraft air contaminants using contaminant analyzers comprising a contaminant collector comprising a membrane and a heater vaporizing captured contaminants; a gravimetric sensor generating a proportionate response when contaminant mass is added to or removed from the sensor, the sensor arranged to receive contaminants desorbed from the membrane when the membrane is heated; a frequency measurement device, measuring the response generated by the sensor as the contaminant is added to and removed from the sensor; a computer readable medium bearing a contaminant recognition program and calibration data; a processor executing the recognition program, the program including a module classifying contaminants by type, and a module using the calibration data for comparison with magnitude of the response generated by the sensor to calculate contaminant concentration; and, a pump, generating flow of aircraft air through the contaminant collector before and after the m

Abstract: Support and drainage materials, filter including the materials, and methods of use are disclosed.

Abstract: Disclosed are porous membranes including a porous support and a coating comprising a copolymer having monomeric units A and B, and optionally monomeric units C; wherein A is a halogenated vinyl monomer other than tetrafluoroethylene, a halogenated alkyl vinyl ether, or an alkene of the formula CnH2n, wherein n is 1-6; B is a perfluoro (alkyl vinyl)ether compound, a perfluoroalkyl vinyl compound, or a perfluoro alkoxyalkyl vinyl ether compound, each compound having one or more sulfonic acid groups or a salt thereof, one or more sulfonyl fluoride groups, one or more sulfonamide groups, or one or more sulfonate ester groups, and C is vinylidene fluoride. Also disclosed are methods of preparing such porous membranes and methods of treating fluids by the use of these membranes.