Patents Assigned to Palleon Pharmaceuticals Inc.
  • Recombinant human sialidases, sialidase fusion proteins, and methods of using the same
    Patent number: 11965188
    Abstract: The invention relates generally to recombinant human sialidases and recombinant sialidase fusion proteins, wherein the sialidase optionally contains one or more mutations compared to wild-type human sialidase, e.g., a substitution, deletion, or addition of at least one amino acid. The invention also provides antibody conjugates including a sialidase and an antibody or a portion thereof. The invention further relates to methods of using the sialidase fusion proteins or antibody conjugates for treating cancer.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: April 23, 2024
    Assignee: Palleon Pharmaceuticals Inc.
    Inventors: Li Peng, Lizhi Cao, Lihui Xu