Abstract: A pump device (10) operable with a syringe (11) having a barrel (12) and a plunger (13). The pump device (10) is operable to cause relative movement between the syringe plunger (13) and the syringe barrel (12) for discharging fluid from the syringe (11). The pump device (10) comprises a portion (31) adapted to engage the syringe barrel (12), and a drive mechanism for moving the syringe plunger (13) relative to the syringe barrel (12) to discharge fluid from the syringe (11). The drive mechanism comprises an actuator (45) adapted to engage the syringe plunger (13) and a power mechanism (61) for moving the actuator (45) to effect movement of the syringe plunger (13) relative to the syringe barrel (12). The pump device (10) thus provides a syringe driving means. There is also provided an infusion system comprising a syringe driving means, the syringe driving means comprising the pump device (10).

Abstract: The present invention relates to unique delivery systems and the use of an imidazobenzodiazepine derivative, such as flumazenil either alone or in combination with other receptor antagonists in the treatment of disease or medical disorders.

Abstract: The present invention relates to unique delivery systems and the use of an imidazobenzodiazepine derivative, such as flumazenil either alone or in combination with other receptor antagonists in the treatment of disease or medical disorders.

Abstract: A pharmaceutical preparation adopted for sustained release of an active agent(s) over an extended period of time at a therapeutic rate without an initial burst release of the agent(s) upon administration, wherein the preparation comprises: (i) an outer portion prepared from one or more layers of a biodegradable polymer, which is selected to release an active agent over an extended period of time when positioned in situ in a patient, and (ii) an inner portion comprising a plurality of micro-capsules formed from at least a biodegradable polymer, said micro capsules containing at least an active agent, wherein the micro-capsules are compressed into the form of a tablet under suitable pressure to suppress the rate of release of the active agent from the micro-capsules.