Patents Assigned to Palumed S.A.
  • Polyquinoline derivatives and the therapeutic use thereof
    Patent number: 8324196
    Abstract: The invention relates to a method for chelating metal ion and/or dissolving amyloid aggregates, including chelating metal ions and/or dissolving amyloid aggregates with a compound of formula (I):
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: December 4, 2012
    Assignees: Palumed S.A., Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Céline Deraeve, Marguerite Pitie, Christophe Boldron, Bernard Meunier
  • NOVEL POLYQUINOLINE DERIVATIVES AND THE THERAPEUTIC USE THEREOF
    Publication number: 20120277265
    Abstract: The invention relates to a method for chelating metal ion and/or dissolving amyloid aggregates, including chelating metal ions and/or dissolving amyloid aggregates with a compound of formula (I):
    Type: Application
    Filed: July 16, 2012
    Publication date: November 1, 2012
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), PALUMED S.A.
    Inventors: Céline DERAEVE, Marguerite Pitie, Christophe Boldron, Bernard Meunier
  • Polyquinoline derivatives and therapeutic use thereof
    Patent number: 8247396
    Abstract: The invention relates to compounds of general formula (I), to the process for the preparation thereof and to the use thereof as a therapeutic agent.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: August 21, 2012
    Assignees: Palumed S.A., Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Celine Deraeve, Marguerite Pitie, Christophe Boldron, Bernard Meunier
  • DUAL MOLECULES CONTAINING A PEROXIDE DERIVATIVE, THEIR SYNTHESIS AND THERAPEUTIC USES
    Publication number: 20120122923
    Abstract: The invention concerns dual molecules corresponding to formula (I): in which: A represents a molecular residue with antimalarial activity of formula (IIa) or (IIIa) or a residue facilitating bioavailability; B represents a cycloalkyl group potentially substituted, or B represents a bi- or tricyclic group capable of being substituted, or B represents 2 cycloalkyl groups linked together through either a single bond or an alkylene chain; m and n represent independently of one another 0, 1 or 2; R5 represents a hydrogen atom, an alkyl, cycloalkyl or C1-3-alkylene-cycloakyl group; Z1 and Z2 represent an alkyl radical, the group Z1+Z2+Ci+Cj representing a mono- or polycyclic structure, with one of the Z1 or Z2 being able to represent a single bond; R1 and R2, identical or different, represent a hydrogen atom or a functional group capable of increasing hydrosolubility; Rx and Ry forming together a cyclic peroxide including 4 to 8 links and including 1 or 2 additional oxygen atoms in the cyclic structure, possibly su
    Type: Application
    Filed: December 11, 2008
    Publication date: May 17, 2012
    Applicants: SANOFI-AVENTIS, PALUMED S.A., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Frederic COSLEDAN, Bernard MEUNIER, Alain PELLET
  • NOVEL POLYQUINOLINE DERIVATIVES AND THERAPEUTIC USE THEREOF
    Publication number: 20090227626
    Abstract: The invention relates to compounds of general formula (I), to the process for the preparation thereof and to the use thereof as a therapeutic agent.
    Type: Application
    Filed: August 4, 2006
    Publication date: September 10, 2009
    Applicant: PALUMED S.A.
    Inventors: Céline Deraeve, Marguerite Pitie, Christophe Boldron, Bernard Meunier
  • Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents
    Publication number: 20070060558
    Abstract: The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q—(Y1)p—(U)p—(Y2)p-A: wherein Q represents an aminoquinoline, (Y1)p(U)p—(Y2)p? is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced.
    Type: Application
    Filed: September 7, 2006
    Publication date: March 15, 2007
    Applicants: PALUMED S.A., Centre National de la Recherche Scientifique (CNRS)
    Inventors: Muriel Sanchez, Bernard Meunier
  • Dual molecules containing peroxy derivative, the synthesis and therapeutic applications thereof
    Publication number: 20070021423
    Abstract: The invention relates to dual molecule compounds containing a peroxide derivative, to processes for the synthesis of such compounds, to pharmaceutical compositions comprising such compounds, and to methods of treatment and prevention of malaria comprising administering such compounds and such pharmaceutical compositions.
    Type: Application
    Filed: May 12, 2006
    Publication date: January 25, 2007
    Applicants: Centre National de la Recherche Scientifique, Palumed S.A., sanofi-aventis
    Inventors: Jerome Cazelles, Frederic Cosledan, Bernard Meunier, Alain Pellet