Patents Assigned to PALVELLA THERAPEUTICS, INC.
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Publication number: 20230263781Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: ApplicationFiled: May 1, 2023Publication date: August 24, 2023Applicant: PALVELLA THERAPEUTICS, INC.Inventors: Wesley Harton KAUPINEN, Braham SHROOT, Simon David BETSON, Charles Rodney GREENAWAY EVANS, Marc Barry BROWN
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Patent number: 11679101Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: GrantFiled: April 7, 2021Date of Patent: June 20, 2023Assignee: PALVELLA THERAPEUTICS, INC.Inventors: Wesley Harton Kaupinen, Braham Shroot, Simon David Betson, Charles Rodney Greenaway Evans, Marc Barry Brown
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Publication number: 20230113775Abstract: Disclosed herein are compositions and methods for topical delivery of EGFR inhibitors. In one embodiment, a topical anhydrous composition includes one or more EGFR inhibitors, one or more solvents, one or more gelling agents, and, optionally, one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: ApplicationFiled: September 8, 2022Publication date: April 13, 2023Applicant: PALVELLA THERAPEUTICS, INC.Inventors: Braham SHROOT, Jeffrey MARTINI, Wesley Harton KAUPINEN
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Patent number: 11617742Abstract: A method of treating or preventing keratin hyperproliferation skin disorders is set forth. The method includes the administration of an mTOR inhibitor to a subject afflicted with the hyperproliferation disorder. The mTOR inhibitor can be administered to the subject via any means known in the art including oral, topical, and transdermal administration.Type: GrantFiled: April 30, 2020Date of Patent: April 4, 2023Assignee: PALVELLA THERAPEUTICS, INC.Inventors: Roger Louis Kaspar, Robyn Patricia Hickerson
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Publication number: 20220016089Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: ApplicationFiled: August 31, 2021Publication date: January 20, 2022Applicant: PALVELLA THERAPEUTICS, INC.Inventors: Wesley Harton KAUPINEN, Braham SHROOT, Simon David BETSON, Charles Rodney GREENAWAY EVANS, Marc Barry BROWN
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Patent number: 11135204Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: GrantFiled: June 18, 2020Date of Patent: October 5, 2021Assignee: Palvella Therapeutics, Inc.Inventors: Wesley Harton Kaupinen, Braham Shroot, Simon David Betson, Charles Rodney Greenaway Evans, Marc Barry Brown
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Publication number: 20210244713Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: ApplicationFiled: April 7, 2021Publication date: August 12, 2021Applicant: PALVELLA THERAPEUTICS, INC.Inventors: Wesley Harton KAUPINEN, Braham SHROOT, Simon David BETSON, Charles Rodney GREENAWAY EVANS, Marc Barry BROWN
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Patent number: 11000513Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: GrantFiled: July 2, 2019Date of Patent: May 11, 2021Assignee: Palvella Therapeutics, Inc.Inventors: Wesley Harton Kaupinen, Braham Shroot, Simon David Betson, Charles Rodney Greenaway Evans, Marc Barry Brown
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Publication number: 20200383956Abstract: A method of treating or preventing keratin hyperproliferation skin disorders is set forth. The method includes the administration of an mTOR inhibitor to a subject afflicted with the hyperproliferation disorder. The mTOR inhibitor can be administered to the subject via any means known in the art including oral, topical, and transdermal administration.Type: ApplicationFiled: April 30, 2020Publication date: December 10, 2020Applicant: PALVELLA THERAPEUTICS, INC.Inventors: Roger Louis Kaspar, Robyn Patricia Hickerson
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Publication number: 20200316034Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: ApplicationFiled: June 18, 2020Publication date: October 8, 2020Applicant: PALVELLA THERAPEUTICS, INC.Inventors: Wesley Harton KAUPINEN, Braham SHROOT, Simon David BETSON, Charles Rodney GREENAWAY EVANS, Marc Barry BROWN
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Patent number: 10722499Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: GrantFiled: January 5, 2018Date of Patent: July 28, 2020Assignee: PALVELLA THERAPEUTICS, INC.Inventors: Wesley Harton Kaupinen, Braham Shroot, Simon David Betson, Charles Rodney Greenaway Evans, Marc Barry Brown
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Publication number: 20200000778Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.Type: ApplicationFiled: July 2, 2019Publication date: January 2, 2020Applicant: PALVELLA THERAPEUTICS, INC.Inventors: Wesley Harton Kaupinen, Braham Shroot