Patents Assigned to PALVELLA THERAPEUTICS, INC.
  • Publication number: 20230263781
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Application
    Filed: May 1, 2023
    Publication date: August 24, 2023
    Applicant: PALVELLA THERAPEUTICS, INC.
    Inventors: Wesley Harton KAUPINEN, Braham SHROOT, Simon David BETSON, Charles Rodney GREENAWAY EVANS, Marc Barry BROWN
  • Patent number: 11679101
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: June 20, 2023
    Assignee: PALVELLA THERAPEUTICS, INC.
    Inventors: Wesley Harton Kaupinen, Braham Shroot, Simon David Betson, Charles Rodney Greenaway Evans, Marc Barry Brown
  • Publication number: 20230113775
    Abstract: Disclosed herein are compositions and methods for topical delivery of EGFR inhibitors. In one embodiment, a topical anhydrous composition includes one or more EGFR inhibitors, one or more solvents, one or more gelling agents, and, optionally, one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Application
    Filed: September 8, 2022
    Publication date: April 13, 2023
    Applicant: PALVELLA THERAPEUTICS, INC.
    Inventors: Braham SHROOT, Jeffrey MARTINI, Wesley Harton KAUPINEN
  • Patent number: 11617742
    Abstract: A method of treating or preventing keratin hyperproliferation skin disorders is set forth. The method includes the administration of an mTOR inhibitor to a subject afflicted with the hyperproliferation disorder. The mTOR inhibitor can be administered to the subject via any means known in the art including oral, topical, and transdermal administration.
    Type: Grant
    Filed: April 30, 2020
    Date of Patent: April 4, 2023
    Assignee: PALVELLA THERAPEUTICS, INC.
    Inventors: Roger Louis Kaspar, Robyn Patricia Hickerson
  • Publication number: 20220016089
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Application
    Filed: August 31, 2021
    Publication date: January 20, 2022
    Applicant: PALVELLA THERAPEUTICS, INC.
    Inventors: Wesley Harton KAUPINEN, Braham SHROOT, Simon David BETSON, Charles Rodney GREENAWAY EVANS, Marc Barry BROWN
  • Patent number: 11135204
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: October 5, 2021
    Assignee: Palvella Therapeutics, Inc.
    Inventors: Wesley Harton Kaupinen, Braham Shroot, Simon David Betson, Charles Rodney Greenaway Evans, Marc Barry Brown
  • Publication number: 20210244713
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Application
    Filed: April 7, 2021
    Publication date: August 12, 2021
    Applicant: PALVELLA THERAPEUTICS, INC.
    Inventors: Wesley Harton KAUPINEN, Braham SHROOT, Simon David BETSON, Charles Rodney GREENAWAY EVANS, Marc Barry BROWN
  • Patent number: 11000513
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: May 11, 2021
    Assignee: Palvella Therapeutics, Inc.
    Inventors: Wesley Harton Kaupinen, Braham Shroot, Simon David Betson, Charles Rodney Greenaway Evans, Marc Barry Brown
  • Publication number: 20200383956
    Abstract: A method of treating or preventing keratin hyperproliferation skin disorders is set forth. The method includes the administration of an mTOR inhibitor to a subject afflicted with the hyperproliferation disorder. The mTOR inhibitor can be administered to the subject via any means known in the art including oral, topical, and transdermal administration.
    Type: Application
    Filed: April 30, 2020
    Publication date: December 10, 2020
    Applicant: PALVELLA THERAPEUTICS, INC.
    Inventors: Roger Louis Kaspar, Robyn Patricia Hickerson
  • Publication number: 20200316034
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Application
    Filed: June 18, 2020
    Publication date: October 8, 2020
    Applicant: PALVELLA THERAPEUTICS, INC.
    Inventors: Wesley Harton KAUPINEN, Braham SHROOT, Simon David BETSON, Charles Rodney GREENAWAY EVANS, Marc Barry BROWN
  • Patent number: 10722499
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: July 28, 2020
    Assignee: PALVELLA THERAPEUTICS, INC.
    Inventors: Wesley Harton Kaupinen, Braham Shroot, Simon David Betson, Charles Rodney Greenaway Evans, Marc Barry Brown
  • Publication number: 20200000778
    Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.
    Type: Application
    Filed: July 2, 2019
    Publication date: January 2, 2020
    Applicant: PALVELLA THERAPEUTICS, INC.
    Inventors: Wesley Harton Kaupinen, Braham Shroot