Abstract: Polypeptides for binding to PD-1 and compositions comprising the same, such as targeting to a cell expressing MAdCAM, which can be used, for example as methods and compounds for conferring site-specific or local immune privilege.
Type:
Application
Filed:
February 23, 2022
Publication date:
September 12, 2024
Applicant:
PANDION OPERATIONS, INC.
Inventors:
Joanne L. VINEY, Nathan HIGGINSON-SCOTT, Kevin OTIPOBY, Salvatore ALIOTO, Lindsay EDWARDS
Abstract: The disclosure relates to methods and compositions for treating Type 1 diabetes, such as compositions comprising an effector domain linked to a protein that binds to MAdCAM.
Type:
Application
Filed:
February 22, 2022
Publication date:
July 11, 2024
Applicant:
PANDION OPERATIONS, INC.
Inventors:
Daniel RIOS, Kevin OTIPOBY, Joanne L. VINEY, Nathan HIGGINSON-SCOTT
Abstract: Methods and compounds for conferring site-specific or local immune privilege, such as to the skin.
Type:
Grant
Filed:
February 18, 2021
Date of Patent:
May 14, 2024
Assignee:
Pandion Operations, Inc.
Inventors:
Daniel Rios, Purvi Mande, Joanne L. Viney, Nathan Higginson-Scott, Kevin Lewis Otipoby, Susmita Borthakur, Salvatore Alioto, Lindsay J. Edwards
Abstract: The disclosure relates to methods and compositions for treating Type 1 diabetes, such as compositions comprising an effector domain linked to a protein that binds to MAdCAM.
Type:
Application
Filed:
February 22, 2022
Publication date:
April 25, 2024
Applicant:
PANDION OPERATIONS, INC.
Inventors:
Daniel RIOS, Kevin OTIPOBY, Joanne L. VINEY, Nathan HIGGINSON-SCOTT
Abstract: Methods and compounds for conferring site-specific or local immune privilege, such as targeting to a cell expressing MAdCAM.
Type:
Grant
Filed:
May 20, 2020
Date of Patent:
August 29, 2023
Assignee:
PANDION OPERATIONS, INC.
Inventors:
Nathan Higginson-Scott, Joanne L. Viney, Kevin Lewis Otipoby, Jyothsna Visweswaraiah, Salvatore Alioto, Lindsay J. Edwards, Erik Sampson, Jacob Glanville, David Maurer, Sarah Ives, Christina Pettus, Lauren Schwimmer