Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of 5-lipoxygenase (5-LO). Also described herein are methods of using such 5-LO inhibitors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions, diseases, or disorders.
Type:
Application
Filed:
September 23, 2010
Publication date:
August 23, 2012
Applicant:
PANMIRA PHARMACEUTICALS, LLC
Inventors:
Jeffrey Roger Roppe, Timothy Andrew Parr, Brian Andrew Stearns
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Grant
Filed:
September 27, 2011
Date of Patent:
August 21, 2012
Assignee:
Panmira Pharmaceuticals, LLC
Inventors:
John Howard Hutchinson, Thomas Jon Seiders, Jeannie M. Arruda
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the antagonists of PGD2 receptors described herein, as well as methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Grant
Filed:
February 12, 2009
Date of Patent:
August 14, 2012
Assignee:
Panmira Pharmaceuticals, LLC
Inventors:
John Howard Hutchinson, Thomas Jonathan Seiders, Brian Andrew Stearns, Bowei Wang, Yen Pham Truong, Jeannie M. Arruda
Abstract: Described herein are ophthalmic pharmaceutical compositions, wherein the ophthalmic pharmaceutical compositions are in a form suitable for administration to an eye of a mammal. Ophthalmic pharmaceutical compositions disclosed herein include at least one DP2 receptor antagonist compound and are used to treat or prevent ophthalmic diseases or conditions.
Type:
Application
Filed:
July 28, 2010
Publication date:
July 19, 2012
Applicant:
PANMIRA PHARMACEUTICALS, LLC
Inventors:
John Howard Hutchinson, Thomas Jon Seiders, Nicholas Simon Stock
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Application
Filed:
November 15, 2011
Publication date:
March 8, 2012
Applicant:
PANMIRA PHARMACEUTICALS, LLC
Inventors:
John Howard HUTCHINSON, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Application
Filed:
October 12, 2011
Publication date:
March 8, 2012
Applicant:
PANMIRA PHARMACEUTICALS, LLC.
Inventors:
John Howard HUTCHINSON, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang, Deborah Volkots
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Application
Filed:
September 27, 2011
Publication date:
January 19, 2012
Applicant:
PANMIRA PHARMACEUTICALS, LLC
Inventors:
John Howard Hutchinson, Thomas Jon Seiders, Bowei Wang, Jeannie M. Arruda, Brian Andrew Stearns
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Grant
Filed:
July 2, 2009
Date of Patent:
December 6, 2011
Assignee:
Panmira Pharmaceuticals, LLC
Inventors:
John Howard Hutchinson, Thomas Jon Seiders, Bowei Wang, Jeannie M. Arruda, Brian Andrew Stearns
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Grant
Filed:
January 29, 2009
Date of Patent:
November 29, 2011
Assignee:
Panmira Pharmaceuticals, LLC
Inventors:
John Howard Hutchinson, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang, Deborah Volkots
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Grant
Filed:
September 28, 2009
Date of Patent:
November 1, 2011
Assignee:
Panmira Pharmaceuticals, LLC
Inventors:
John Howard Hutchinson, Nicholas Simon Stock, Jeffrey Roger Roppe, Jill Melissa Scott, Brian Andrew Stearns, Yen Pham Truong, Deborah Volkots, Timothy Parr
Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
Type:
Grant
Filed:
November 5, 2009
Date of Patent:
October 11, 2011
Assignee:
Panmira Pharmaceuticals, LLC
Inventors:
John Howard Hutchinson, Brian Andrew Stearns, Jill Melissa Scott