Abstract: The present invention relates to topical formulations comprising a compound of the following formula: for treating ocular neovascularization. The Compound-I is present in a solution or a suspension in about 0.005% to about 5.0% w/v, such that the solution or suspension delivers the compound at the posterior segment of the eye for inhibiting VEGF in the retina and/or the choroid.
Type:
Grant
Filed:
July 23, 2018
Date of Patent:
June 4, 2019
Assignee:
PanOptica, Inc.
Inventors:
David P. Bingaman, Paul G. Chaney, Martin B. Wax
Abstract: The present invention relates to topical formulations comprising a compound of the following formula: for treating ocular neovascularization. The Compound-I is present in a solution or a suspension in about 0.005% to about 5.0% w/v, such that the solution or suspension delivers the compound at the posterior segment of the eye for inhibiting VEGF in the retina and/or the choroid.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
October 9, 2018
Assignee:
PanOptica, Inc.
Inventors:
David P. Bingaman, Paul G. Chaney, Martin B. Wax
Abstract: The present application relates to topical formulations comprising Compound-I or its free base, and a second active agent selected from nicotinic acid, nicotinamide, and vitamin K, and a combination thereof, for treating ocular neovascularization. The present application also relates to pharmaceutical compositions comprising particles of Compound-I or its free base, and suspension formulations comprising the particle compositions of Compound-I or its free base.
Type:
Grant
Filed:
September 17, 2015
Date of Patent:
November 14, 2017
Assignee:
PanOptica, Inc.
Inventors:
David P. Bingaman, Paul G. Chaney, Martin B. Wax
Abstract: The present application relates to topical formulations comprising Compound-I or its free base, and a second active agent selected from nicotinic acid, nicotinamide, and vitamin K, and a combination thereof, for treating ocular neovascularization. The present application also relates to pharmaceutical compositions comprising particles of Compound-I or its free base, and suspension formulations comprising the particle compositions of Compound-I or its free base.
Type:
Grant
Filed:
March 25, 2016
Date of Patent:
April 18, 2017
Assignee:
PanOptica, Inc.
Inventors:
David P. Bingaman, Paul G. Chaney, Martin B. Wax
Abstract: The present invention relates to topical formulations comprising a compound of the following formula: for treating ocular neovascularization. The Compound-I is present in a solution or a suspension in about 0.005% to about 5.0% w/v, such that the solution or suspension delivers the compound at the posterior segment of the eye for inhibiting VEGF in the retina and/or the choroid.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
September 20, 2016
Assignee:
PanOptica, Inc.
Inventors:
David P. Bingaman, Paul G. Chaney, Martin B. Wax