Patents Assigned to Pantherix, Ltd.
  • 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents
    Patent number: 6916803
    Abstract: The present invention relates to novel Syn isomers of racemates and optical isomers of 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids of the following formula: and their use in treating infections caused by gram-negative pathogenic bacteria.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: July 12, 2005
    Assignee: Pantherix, Ltd.
    Inventors: Ronald George Micetich, Samarendra Maiti, Charles Fiakpui, George Thomas, Andhe V. Narender Reddy, Sameeh M. Salama, Rajeshwar Singh
  • Production and use of antimicrobial agents
    Patent number: 6696268
    Abstract: A method for identifying antimicrobial agents comprises the steps of: (i) contacting a sample containing non-mammalian PPAT enzyme with a suitable substrate and a potential antimicrobial or antiprarasitic agent, under suitable conditions; (ii) measuring the activity of the PPAT enzyme; (iii) comparing the activity of the enzyme to that of a reference sample lacking the agent; and (iv) selecting an agent that reduces the activity of the PPAT enzyme.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: February 24, 2004
    Assignee: Pantherix, Ltd.
    Inventors: William Vare Shaw, Ann Lewendon