Abstract: A method and apparatus that enables a user to sort data from one or more sample lots, which may be obtained via a network, such as the Internet, into a composite parameter structure. The composite parameter structure is a function of one or more parameters corresponding to one or more characteristics associated with one or more sample lots. The composite parameter structure representation may be printed, stored, or transmitted to another location. A server device that is coupled and working in conjunction with a client device may implement the present invention.
Type:
Grant
Filed:
May 14, 2009
Date of Patent:
August 9, 2011
Assignee:
Par Pharmaceutical, Inc.
Inventors:
Robert Ruemer, Narayan Ragunathan, Robert A. Femia
Abstract: A stable pharmaceutical mercury-free aqueous solution of cyanocobalamin comprised of cyanocobalamin and water wherein said solution of cyanocobalamin is suitable for intranasal administration, has a viscosity less than about 1000 cPs, and wherein said solution of cyanocobalamin has a bioavailability of cyanocobalamin when administered intranasally of at least about 7% relative to an intramuscular injection of cyanocobalamin with the proviso that the solution is essentially free of mercury and mercury-containing compounds. The present invention is also directed towards a method for elevating the vitamin B12 levels in the cerebral spinal fluid (CSF) comprising administering intranasally a sufficient amount of a mercury-free cyanocobalamin solution so as to increase the average ratio of vitamin B12 in the CSF to that in the blood serum (B12 CSF/B12 Serum×100) to at least about 1.
Type:
Grant
Filed:
March 27, 2008
Date of Patent:
February 1, 2011
Assignee:
Par Pharmaceutical, Inc.
Inventors:
Steven C. Quay, Peter C. Aprile, Zenaida O. Go, Anthony P. Sileno
Abstract: Compositions suitable for intranasal administration containing calcitonin, chlorobutanol, a pH of about 3.5, and sodium chloride, and an intranasal spray and a pharmaceutical delivery device thereof.
Type:
Grant
Filed:
March 22, 2004
Date of Patent:
October 12, 2010
Assignee:
Par Pharmaceutical, Inc.
Inventors:
Steven C. Quay, Jorge C. de Meireles, Arati A. Deshpande, Zenaida O. Go, Anthony P. Sileno
Abstract: A method and apparatus that enables a user to sort data from one or more sample lots, which may be obtained via a network, such as the Internet, into a composite parameter structure. The composite parameter structure is a function of one or more parameters corresponding to one or more characteristics associated with one or more sample lots. The composite parameter structure representation may be printed, stored, or transmitted to another location. A server device that is coupled and working in conjunction with a client device may implement the present invention.
Type:
Application
Filed:
May 14, 2009
Publication date:
November 19, 2009
Applicant:
Par Pharmaceutical, Inc.
Inventors:
Robert Ruemer, Narayan Ragunathan, Robert A. Femia
Abstract: A method and apparatus that enables a user to sort data from one or more sample lots, which may be obtained via a network, such as the Internet, into a composite parameter structure. The composite parameter structure is a function of one or more parameters corresponding to one or more characteristics associated with one or more sample lots. The composite parameter structure representation may be printed, stored, or transmitted to another location. A server device that is coupled and working in conjunction with a client device may implement the present invention.
Type:
Grant
Filed:
June 6, 2007
Date of Patent:
June 23, 2009
Assignee:
Par Pharmaceutical, Inc.
Inventors:
Robert Ruemer, Narayan Ragunathan, Robert A. Femia
Abstract: A method and apparatus that enables a user to sort data from one or more sample lots, which may be obtained via a network, such as the Internet, into a composite parameter structure. The composite parameter structure is a function of one or more parameters corresponding to one or more characteristics associated with one or more sample lots. The composite parameter structure representation may be printed, stored, or transmitted to another location. A server device that is coupled and working in conjunction with a client device may implement the present invention.
Type:
Grant
Filed:
June 10, 2005
Date of Patent:
July 17, 2007
Assignee:
PAR Pharmaceutical, Inc.
Inventors:
Robert Ruemer, Narayan Ragunathan, Robert A. Femia
Abstract: Pharmaceutical compositions for treating hyperlipidemia or hypercholesterolemia in mammals are described which comprise: 1 (a) fenofibrate 5 to 35 wt. -% (b) a cyclodextrin 4 to 30 wt. -% (c) an alkali metal or 0.1 to 10 wt. -%; and alkaline earth metal docusate and/or alkali metal or alkaline earth metal lauryl sulfate (d) a water-insoluble, wettable 5 to 30 wt. -% inorganic carrier capable of forming a dispersion of the fenofibrate and a pharmaceutically acceptable inert carrier or diluent.
Type:
Application
Filed:
January 16, 2003
Publication date:
July 22, 2004
Applicant:
PAR PHARMACEUTICAL INC.
Inventors:
Robert A. Femia, Oscar I. Fishkis, Damodar P. Patel, Narayan Ragunathan
Abstract: This application relates to a process for the preparation of the cyanomethyl ester
which comprises reacting 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid or a salt thereof, with a haloacetonitrile of the formula XCH2CN wherein X is Cl, Br, or I.
Type:
Grant
Filed:
July 23, 2001
Date of Patent:
July 15, 2003
Assignee:
Par Pharmaceutical, Inc.
Inventors:
Arie L. Gutman, Genady Nisnevich, Eleonora Shkolnik, Igor Zaltzman, Boris Tishin