Patents Assigned to Paradigm Genetics, Inc.
  • Modified full length promoters
    Patent number: 6331663
    Abstract: This invention relates to plants, seeds and DNA constructs containing DNA that is either SEQ ID NO:10, SEQ ID NO:11, or SEQ ID NO:20, or the complementary or double stranded sequence thereof, as well as a method for their preparation.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: December 18, 2001
    Assignee: Paradigm Genetics, Inc.
    Inventor: Andreas S. Kloti
  • Methods for determining deoxyxylulose 5-phosphate synthase activity
    Patent number: 6326164
    Abstract: The invention is directed to methods and compositions for the determination of deoxyxylulose 5-phosphate synthase (DXPS) activity. The methods and compositions of the invention are amenable to high-throughput screening assays for the identification of inhibitors and enhancers of DXPS activity. Such compounds have use in the modulation of plant and microbial growth. The compositions of the invention are DXPS fragments and chimeric polypeptides that have increased solubility as compared to the wild-type DXPS polypeptide. These DXPS fragments and chimeric polypeptides can be recombinantly expressed and purified in quantities suitable for high-throughput screening assays. The assays of the invention are based on the detection of substrates of DXPS that remain after a DXPS reaction.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: December 4, 2001
    Assignee: Paradigm Genetics, Inc.
    Inventors: John W. Rice, Andreas S. Kloti, John M. Crawford, Jr., Beth Lanning, Sandy J. Stewart
  • Method of determining activity of 1-deoxy-D-xylulose-5-phosphate reductoisomerase and 1-deoxy-D-xylulose-5-phosphate synthase
    Patent number: 6303365
    Abstract: The invention relates to DNA which encodes Arabidopsis 1-deoxy-xylulose-5-phosphate reductoisomerase and to a method of identifying modulators of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase and 1-deoxy-D-xylulose-5-phosphate synthase activity.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: October 16, 2001
    Assignees: Paradigm Genetics, Inc. R.T.P, Bayer Ag
    Inventors: William Frank Martin, Ruediger Hain, Klaus-Guenther Tietjen, Marco Busch, Andreas S. Kloti