Abstract: The invention relates to a composition, method and apparatus for determining the sequence of a nucleic acid strand utilizing a pH-sensing agent.

Abstract: The present invention relates generally to encoding samples. More specifically, it relates to barcodes and compositions involving upconverters and methods including them. In a composition aspect of the invention, a composition comprising two or more lanthanide materials is provided. Each lanthanide material comprises a host, an absorber, and an emitter, and the materials emit detectable electromagnetic radiation upon excitation with absorbable electromagnetic energy. One or more relative ratios of emission intensities uniquely identify the composition.

Abstract: The invention relates to a composition, method and apparatus for determining the sequence of a nucleic acid strand utilizing a pH-sensing agent.

Abstract: Methods and devices for marking objects include the use of a dimensionally hierarchical series of submicron sized features to emboss, mold, and/or print markings into objects. The markings may include security features, codes, numbers, symbols, signs and any combinations thereof. The markings may be used for identification, authentication or attribution of the item.

Abstract: A microcontact printing pin for depositing a liquid on a substrate includes a printing tip at a first end and a reservoir, which holds a supply of a printing fluid, communicating with the printing tip. A fluid delivery channel extends between the reservoir and the printing tip and the channel has a tapered shape decreasing in width from the reservoir to the printing tip. This tapered shape ensures that the delivery of the printing fluid to the printing tip is smooth, accurate and controllable. The printing tip portion may also be thinned so that the printing tip portion is thinner than the portion provided with the reservoir and a stepped portion between the reservoir and the thinned printing tip portion that eliminates prespotting.

Abstract: Crystallization Photoresist (PR) apparatus and methods which allow for fast screening and determination of protein crystallization conditions with small protein quantities and rapid crystallization. The apparatus comprise a first region comprising a first nucleation catalyst material and a second region comprising a second nucleation catalyst material, with the first and second regions positioned adjacent to each other and configured to support at least one crystal, and with the first region having a variation in a nucleation property of the first nucleation catalyst material in the first region. The crystal may be supported at an interface of the adjacent regions.