Abstract: Methods of treating a host suffering from obesity or an overweight condition are provided. Methods of preventing obesity or an overweight condition are also provided. The methods include delivery of a hypoestoxide, hypoestoxide derivative or hypoestoxide agonist, or hypoestes dried leaf powder to a host suffering from obesity or an overweight condition or a host at risk for developing obesity or becoming overweight. The methods further include the administration of a chemotherapeutic agent, such as a non-steroidal anti-inflammatory drug, in combination with delivery of a hypoestoxide, hypoestoxide derivative or hypoestoxide agonist, or hypoestes dried leaf powder.

Abstract: Methods for treatment and prophylaxis of hyperlipidemias, including hypertriglyceridemia and hypercholesterolemia, are provided. The methods include administering to a host a therapeutically or prophylactically effective amount of a diterpene compound, such as a hypoestoxide.

Abstract: Novel enhanced usage of hypoestoxides derivatives and agonists theeof as active agents against nucleated infectious entities including known parasites and the like microbiological insultors of living tissue, systems and organisms, known modes of administration and related compounds are used alone or in combination with the instant teachings.