Abstract: Methods of treating a host suffering from restenosis are provided. The methods include delivery of a stent coated with a hypoestoxide, hypoestoxide derivative or hypoestoxide agonist compound to a vessel. The methods further include the administration of a chemotherapeutic agent in combination with delivery of a stent coated with a hypoestoxide, hypoestoxide derivative or hypoestoxide agonist compound to a vessel. The chemotherapeutic agent may be coated on the stent or administered systemically.
Type:
Application
Filed:
June 23, 2004
Publication date:
December 23, 2004
Applicant:
Paraquest Medivice, Inc.
Inventors:
Emeka J. Nchekwube, Emmanuel A. Ojo-Amaize, Howard B. Cottam