Abstract: A lamp having a first module for being attached to a ceiling or wall element, a second module connected to the first module and being rotatable with respect to the first module along a first axis, a third module having one or more light-emitting elements, the third module being connected to the second module and rotatable with respect to the second module along a second axis, the second axis being substantially perpendicular to the first axis.

Abstract: Methods and apparatuses for extensible stylesheet design using meta-tag information are disclosed. A designed stylesheet is for transferring content-oriented markup language files into a target file so as to support various presentations and information exchange. According to one aspect, a data processing mechanism starts with inserting meta-tag declarations in a target file wherein the meta-tag information pertains to information between dynamic objects in the target file and a source file. The target file with meta-tag information is then converted into one or more extensible stylesheets.

Abstract: Surgical instrument for endoscopic surgery that permits the simulation of the articulation movements of a surgeon finger, comprising a rigid tube (3) whose distal end has a first phalanx (4) articulated, being in turn articulated to a second phalanx (5), which is linked to the rigid tube (3) by means of cables housed in cross ducts (12), situated in the interior of the first phalanx (4), linking the movement of the second phalanx (5) to that of the first phalanx (4), whose articulation takes place due to the actuation of the transmission rod (11), the rigid tube (3) being attachable to a handle (1) that incorporates a controller (2) for the actuating of the instrument articulation movement by the surgeon, which operates a fork (14), which in turns actuates the transmission rod (11).

Abstract: A lead for an implantable cardiac prosthesis, with protection against the thermal effects of MRI fields by terminating the lead head (10) with an electrically insulating tubular outer housing (28) and an anchoring mechanism. The tubular housing (28) carries an electrically isolated thermally conductive solid part in the outer region of its distal end forming a heat sink. The heat sink thermally conductive material is for example titanium, associated with an electrically insulating coating such as a diamond deposition. The anchor may be a projecting helical anchoring screw (20), axially extending the tubular housing, which is an electrically conductive active screw on at least one end portion.

Abstract: A connector for a multipolar lead having a substantially cylindrical cavity that contains a stack (200) of alternating annular electrical contact elements (210) and annular isolation elements (220). The isolation elements (220) comprise an annular rigid sleeve and an annular flexible seal disposed against an annular face in an interior region of the rigid sleeve. The flexible seal extends axially from one lateral side of the rigid sleeve to the other in the interior region of the rigid sleeve. The sleeve and the seal include are immobilized relatively to each other in the axial direction by use of mating surface profiles respectively defined on an inner annular side of the sleeve and on an outer annular side of the flexible seal. In addition, each lateral side of the flexible seal is projecting with respect to the corresponding lateral sides of the rigid sleeve.

Abstract: A lead for an implantable cardiac prosthesis, having an integrated protection against the effects of magnetic resonance imaging (“MRI”) fields. A protection circuit (26), placed at the distal end of the lead comprises a resistive component (28) interposed between the electrode (E1, E2) and the distal end of the conductor (22, 24) associated with this electrode. A normally-open controlled active switch (34, 36), allows in its closed state to short-circuit the resistive component. A control stage. (32) is coupled to the conductors and detects the voltage of a stimulation pulse applied on the conductor(s), and selectively controls by this voltage the closing of the active switch for a duration at least equal to the duration of detected stimulation pulse.

Abstract: An electrical connection plug for a multipolar lead of an active implantable medical device. This plug has a cylindrical outer surface including a plurality of annular electrical contact zones axially separated and formed of conductive cylindrical rings (101, 102, 103), the electrical contact zones being alternatively separated by a plurality of intercalary insulating cylindrical zones. The plug includes an insulating monobloc core (200) of a generally cylindrical shape having a plurality of cylindrical side surfaces (213a) for coaxial centering, a conductive ring being placed on at least one centering side surface. The central core also includes housings for receiving conductive pods (240) on which connection wires (21, 22) are welded, a pod being welded to a conductive ring.

Abstract: Surgical instrument for endoscopic surgery that permits the simulation of the articulation movements of a surgeon finger, comprising a rigid tube (3) whose distal end has a first phalanx (4) articulated, being in turn articulated to a second phalanx (5), which is linked to the rigid tube (3) by means of cables housed in cross ducts (12), situated in the interior of the first phalanx (4), linking the movement of the second phalanx (5) to that of the first phalanx (4), whose articulation takes place due to the actuation of the transmission rod (11), the rigid tube (3) being attachable to a handle (1) that incorporates a controller (2) for the actuating of the instrument articulation movement by the surgeon, which operates a fork (14), which in turns actuates the transmission rod (11).

Abstract: An energy harvester device for an autonomous intracorporeal leadless capsule having an outside surface (42) on the body (40) of the capsule, that is deformable under the effect of pressure variations in the environment surrounding the capsule. A first capacitor electrode coupled to the deformable surface and a mechanical damping element (68) form a high-pass filter with respect to the pressure variations, and a second capacitor electrode (54) is mounted on a support (56) connected to the body. The deformable surface movement produces a correlative modification of the spacing between the two electrodes with a correlative variation of the capacity of said capacitor. The capacitor is preloaded when its capacity is maximum, it is unloaded by transferring its energy into a storage circuit when this capacity decreases under the effect of a reduction in the opposing surfaces and/or of an increase of the dielectric gap.

Abstract: A method for quantification of the desynchronization between the clocks of two medical devices communicating wirelessly, for example, by HBC signals. The devices are separately clocked by slow clocks (CLK1/32k, CLK2/32k) and include selectively activated fast clocks (CLK1/10M, CLK2/10M). The method comprises: a) on a predetermined transition (T1) of a slow clock, transmission by one device of a synchronization query signal (SYNC) to the other device, b) counting of the pulses of the activated fast clock to detect a predetermined transition (T3) of the first slow clock, then c) transmitting from the other device to the first device a response signal (D1) and d) upon reception of the response signal, computing a temporal shift (OFFSET) according to the result (D1, D2) of the counting of the pulses of the fast clock. Two fast clocks, one on each device, also can be used.

Abstract: The method comprising: a) obtaining a gene sequence codifying a naturally occurring aminoacyl-tRNA synthetase; b) engineering the gene codifying for said aminoacyl-tRNA synthetase, resulting into an aminoacyl-tRNA synthetase with a defective activity, with the proviso that the engineering does not affect the functionality of the catalytic site of the enzyme; c) cloning the gene resulting from step (b) in an expression vector; d) transforming isolated mammalian cells with the expression vector resulting from step (c); e) growing the recombinant cells resulting from step (d) in a nutrient medium under conditions which allow the expression of the engineered aminoacyl-tRNA synthetase, resulting the expression into cell death or a decrease in the rate of cell division; f) providing a substance to be tested to the medium resulting from step (e); and g) analyzing the resulting cell growth, wherein if there is an increase in cell growth, then the substance selectively inhibits the activity of the engineered aminoacyl

Abstract: A subject of the invention is a method for discriminating between and counting at least two populations of biological elements carrying specific characteristics, optionally present in a sample. The invention allows the clear and unambiguous detection of at least three populations of biological elements by the use of only two detection means, which means that at least two populations of biological elements are detected by one and the same detection means. The invention can be carried out if three different probes are used, each recognizing and becoming fixed to one of the populations of biological elements to be detected, each of the probes being itself rendered detectable by a different marker, two of said markers having two emission spectra having at least one common part (overlapping emission spectra) and the third having an emission spectrum having essentially no part in common with the other two (non-overlapping spectrum).

Abstract: A device for dispersing a sample of dry powder onto a surface in a dispersion chamber. The device includes a dispersion chamber situated in an environment, and a pressure source that provides a pressure difference between the environment and an inside of the dispersion chamber. The surface is positioned in the dispersion chamber. The sample of dry powder is introduced into the dispersion chamber through a membrane that is interposed between the environment and the inside of the dispersion chamber and on which the sample is disposed. The membrane is rupturable so as to open into the dispersion chamber when a predetermined pressure difference across the membrane is exceeded. This permits entry of a fluid in the environment through the ruptured membrane, and movement of the dry powder sample in an evenly dispersed manner without producing an ordered movement of powder grains in the dispersion chamber.

Abstract: A method of bonding a first substrate to a second substrate by molecular bonding by forming an insulating layer on the bonding face of the first substrate, chemical-mechanical polishing of the insulating layer, activating a bonding surface of the second substrate by plasma treatment, etching an exposed surface of the insulating layer, and bonding together the two substrates together by molecular bonding wherein the etching is conducted after the chemical-mechanical polishing and before the bonding.

Abstract: A device (1) for use in the surgical treatment of a patient suffering from funnel chest characterised in that it comprises a plate adapted to be fitted underneath the skin of the patient, and further characterised in that, in use, said plate can be attached to the patient's sternum and the curvature, length and width of the plate being such that the plate extends on both sides of the sternum and on the outside of the patient's thorax and is supported by the ribs to hold up the sternum.

Abstract: Cytotoxic anti-LAG-3 monoclonal antibodies or fragments thereof causing depletion of LAG-3+ activated T cells are described, as are related pharmaceuticals and methods of treating. Also described are related nucleic acid and protein sequences.

Abstract: A mobile imaging system includes an erasable medium and an imaging device. The erasable medium can be a UV imageable photochromic medium. The imaging device includes an input for generating imageable content in the device, a sensor for detecting and interpreting interaction of the device with respect to an imageable surface of the erasable medium, and an imaging component, responsive to the sensor, for outputting the generated content onto the imageable surface of the erasable medium.

Abstract: A method for producing an epitaxial layer. First, a structure is fabricated by: formation of an intermediate layer on a donor substrate; and formation of the epitaxial layer on the intermediate layer by epitaxy; with the melting temperature of the intermediate layer being lower than the melting temperature of the epitaxial layer; and then a detachment step for transferring the epitaxial layer from the donor substrate. The detachment step includes applying at least one thermal treatment performed at a temperature of between the melting temperature of the intermediate layer and the melting temperature of the epitaxial layer.

Abstract: An educational recommender system and a method are provided. The method includes receiving a request to recommend a course of action related to a plurality of current students; accessing a computer database storing student data that corresponds to the plurality of current students; clustering in a computer process the plurality of current students into at least two clusters based at least on granular assessment data associated with student data corresponding to respective current students; and outputting the results of the clustering to a user. The granular assessment data includes a result of an assessment administered to respective students of the plurality of current students, and each assessment includes a plurality of questions for assessing one of the current students. The associated result includes an independent evaluation of each respective question of the plurality of questions.

Abstract: A recommender system and method including receiving a request identifying at least one current student for which a recommendation is sought and accessing stored student data including attributes associated with respective students of the current students and a plurality of predecessor students. For the predecessor students the attributes include educational resources. The method includes clustering one of predecessor students and the current students into clusters based on sameness of first selected attributes of their respective associated attributes. The method includes generating a mapping between respective students of the other of the predecessor and current students and one of the clusters based on sameness of second selected attributes associated with the students being mapped. The method then includes recommending for each of the current students the educational resource associated with the predecessor student or cluster of predecessor students that the current student is mapped with.