Abstract: The invention describes an aerosol generator for inhalation therapy devices, in which an oscillatable assembly, consisting of at least a membrane and an oscillation generator, is mounted in an encapsulating means such that at least the membrane is exposed for the supply of liquid and the generation of an aerosol, whereas the remaining parts of the oscillatable assembly are protected. Mounting occurs by means of a flexible passage such that the oscillatory motions of the oscillatable assembly are not negatively affected.

Abstract: The inventive inhalation therapy device (1) is designed in such a manner that the temperature of a liquid to be nebulized is measured and is taken into account in the form of nebuliztion schemata during the nebuliztion of the liquid.

Abstract: To increase the accuracy of the administration of doses of inhalation therapies for animals, the invention proposes a two-part inhalation mask for animals in which each mask part (9) comprises an aerosol chamber (1) and an adaptation chamber (2). The two chambers are separated by a dividing wall (3) with an opening for the aerosol so that during the inhalation phases, the aerosol passes together with the respiratory air out of the aerosol chamber (1) into the adaptation chamber (2).

Abstract: The invention relates to an inhalation therapy apparatus comprising an aerosol generating device (1, 6, 7) for atomizing a liquid (3), a connecting device (8, 9) for supplying a control signal, and a control device (10) from which a control signal of the connecting device can be supplied to the aerosol generating device whereby causing the aerosol generating device to atomize the liquid. To this end, an output signal, which is elicited by the breathing of the patient on the connecting device (8, 9) of the aerosol generating device (1, 6, 7) is supplied to the control device (10) for controlling the inhalation therapy apparatus.

Abstract: The invention relates to a device for detecting the parameters of an aerosol, in particular in inhalation therapy devices, whereby light is shone through a translucent material but not through a transparent material in a detection region and is detected and analysed by means of two receivers.

Abstract: The invention relates to an inhalation therapy device including a membrane aerosol generator. A detection device is provided for determining whether a liquid to be atomized is available. In the absence of liquid, the activation of the membrane aerosol generator is interrupted and/or a signal is output.

Abstract: The invention is in the field of pharmaceutical dosage forms, and more particularly in the field of pharmaceutical granules and processes for making granules. The invention provides a process for preparing pharmaceutical granules which contain an active ingredient in the form of a salt, said process comprising the steps of (a) providing a powder containing the active ingredient as a free base or acid, and (b) agglomerating the powder by adding a granulation liquid to form granules; wherein step (b) is conducted in the presence of a neutralization agent capable of neutralizing the active ingredient, and for a sufficient amount of time to allow the active ingredient to become at least partially converted into a salt. The invention also provides pharmaceutical granules obtainable by said process and pharmaceutical compositions comprising said granules. The invention further provides the use of pharmaceutical granules for the pulmonary delivery of an active ingredient.

Abstract: An inhalation nebulizer includes an aerosol generator that has a diaphragm vibrated by a vibration generator. The inhalation nebulizer includes a liquid storage container that is in fluid contact with the diaphragm. A liquid contained in the storage container is atomized into a mixing chamber through openings in the diaphragm and can subsequently be inhaled by a patient.

Abstract: An inhalation therapy device for providing a medicament in the form of an aerosol for inhalation, said device comprising a storage means for a medicament, which enables an improved deposition of medicament droplets in the respiratory tract of a patient. The inhalation therapy device comprises a first electric contact means which is in contact with the medicament and a second electric contact means which is in contact with the patient, wherein by applying a voltage it is possible to cause an electrostatic charge between the medicament and the patient, which leads to an improved deposition of the medicament in the respiratory tract of a patient.

Abstract: The invention relates to an aerosol generator that comprises an oscillating membrane that is provided with openings. The aerosol generator is further characterized in that the liquid container is impinged upon with negative pressure by displacing a sealing element using a slidable sleeve and a rotary sleeve.

Abstract: An inhalation nebulizer (1) includes an aerosol generator (2) that has a diaphragm (22) vibrated by a vibration generator (23). The inhalation nebulizer (1) includes a liquid storage container (21) that is in fluid contact with the diaphragm (22). A liquid contained in the storage container (21) is atomized into a mixing chamber (3) through openings in the diaphragm and can subsequently be inhaled by a patient.

Abstract: Sterile compositions for administration as aerosols are described. They contain an active agent which is poorly water-soluble, a non-ionic surfactant acomponent and a phospholipid component. The compositions are suitable for oral or nasal inhalation, but also for topical or oromucosal administration. They are particulary useful for the efficient pulmonary administration of poorly soluble corticosteroids and can be aerosolized with common nebulizers.

Abstract: An aerosol generation device comprising an oscillatable membrane (1) for the nebulization of a liquid, having a first curved region (11), and an oscillation generating device (2, 3) by which the membrane can be caused to oscillate such that a liquid disposed on one side of the membrane is nebulized through the oscillating membrane and is present on the other side of the membrane as an aerosol. The membrane has at least a second region (12) which is surrounded by the first region (11). The first region (11) and the second region (12) have different curvatures (1/r1, 1/r2).

Abstract: The invention relates to a device for inhalation therapy. Said device comprises an aerosol-producing device for spraying a liquid (3), preferably comprising a membrane (1), a support unit (6), an electromechanical transducer unit (7), and a connecting device (8,9) for supplying an oscillation control signal. The inventive device also comprises a control device (10) from which an oscillation control signal can be supplied to the connecting device of the aerosol-producing device, such that the aerosol-producing device sprays the liquid. Another control signal is supplied to the aerosol-producing device (1,6,7), moving the membrane (1) in oscillation in an audible frequency range, thus causing the emission of audible signals for a user.

Abstract: To increase the accuracy of the administration of doses of inhalation therapies for animals, the invention proposes a two-part inhalation mask for animals in which each mask part (9) comprises an aerosol chamber (1) and an adaptation chamber (2). The two chambers are separated by a dividing wall (3) with an opening for the aerosol so that during the inhalation phases, the aerosol passes together with the respiratory air out of the aerosol chamber (1) into the adaptation chamber (2).

Abstract: Metering aerosol dispensing device comprising an aerosol container (23); a nozzle (31, 32) that is arranged in a nozzle body (30), whereby the aerosol is dispensed via said nozzle when the aerosol container (23) is pushed against the body (30) of the nozzle once the metering aerosol dispensing device is actuated; a meter (1, 2, 4) that counts the number of times that the metering aerosol dispensing device is actuated; and an actuating device (10) that enables the meter (1, 2, 3, 4) to move forward when the metering aerosol dispensing device is actuated. The invention is characterized in that the actuating device (10) is designed and arranged in the metering aerosol dispensing device in such a way that the body (30) of the nozzle is accomodated in the interior of the actuating device (10) and the nozzle (31) is released in order to produce aerosol in an unrestricted manner.

Abstract: The invention describes a mouthpiece for an inhalation therapy unit wherein an aerosol for inhalation is prepared for a patient, said mouthpiece comprising a substantially tubular base (1), in the wall of which an orifice (2) is formed, and a flat, elastic valve member (3), which is adapted in dimension and shape to the orifice (2) for the closing thereof and which is secured to the mouthpiece in such a manner that during an inspiration process through the mouthpiece the orifice (2) is closed and during an expiration process directed into the mouthpiece the orifice (2) is opened. According to the invention, at least one enlarged contact surface (6, 8, 11, 13, 15, 16) is provided at the orifice (2) for the accumulation and holding of an amount of liquid by adhesion.

Abstract: The invention describes an inhalation or breathing mask for therapeutic nebulisers, in which around a connecting socket 4 for the therapeutic nebuliser is arranged an exhalation valve consisting of exhalation openings and a flexible valve element. The exhalation openings 7 are formed by exhalation channels 8 and can be closed individually by closure devices, for example stoppers, in order to set a predefined exhalation resistance.

Abstract: In an inhalation therapy apparatus a limiter section is provided in the air supply duct which serves as the limiting element for the movement of a valve element of an inlet valve. In the limiter section are provided openings through which surrounding air can flow when the valve element rests against the front edge of the limiter section facing the valve element.