Patents Assigned to PARIS SCIENCES ET LETTRES
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Patent number: 11945930Abstract: Organic solid three-dimensional polymeric foams, a process for preparing the same, and use thereof, the foams includes a solid continuous phase and pores, wherein the foams have a pore size ranging from 50 nm to 200 ?m and a volumetric fraction of the solid continuous phase is from 0.1 to 60%, with respect to the total volume of the foams, and a polydispersity index from 1 to 30%, the foams being ordered over a volume of at least 100 pores.Type: GrantFiled: October 9, 2020Date of Patent: April 2, 2024Assignees: PARIS SCIENCES ET LETTRES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLE DE LA VILLE DE PARISInventors: Ilham Maimouni, Maria Russo, Janine Cossy, Patrick Tabeling
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Patent number: 11920998Abstract: The present invention relates to microfluidic or millifluidic chips (1) comprising at least one pressure sensing unit (4) able to measure a fluid flow pressure. The present invention also relates to a method for a direct and contact-free measuring of a local pressure of a fluid circulating in a microfluidic circuit, using a microfluidic or millifluidic chips (1) according to the invention.Type: GrantFiled: December 18, 2020Date of Patent: March 5, 2024Assignees: PARIS SCIENCES ET LETTRES, École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris, Centre National de la Recherche Scientifique, Sorbonne Université, Université Paris CitéInventors: Anke Lindner, Lucie Ducloué, Md. Anamul Haque, Jian-Ping Gong
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Publication number: 20230212700Abstract: A portable diagnostic device for performing the diagnosis of pathogens, such as viruses, bacteria, microorganisms, etc., by rapidly detecting their nucleic acids in a biological sample to be tested. Also, the use of the portable diagnostic device and the methods for detection of at least one nucleic acid sequence of interest implemented with the aid of the portable diagnostic device.Type: ApplicationFiled: April 9, 2021Publication date: July 6, 2023Applicants: PARIS SCIENCES ET LETTRES, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Patrick TABELING, Pierre GARNERET, Elian MARTIN, Etienne COZ, Elodie BRIENT-LITZLER, Jean-Claude MANUGUERRA, Jessica VANHOMWEGEN
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Patent number: 11661662Abstract: The present invention relates to an electrode comprising an electrically conductive substrate of which at least one portion of the surface is covered with a metal deposit of copper, the surface of said deposit being in an oxidised, sulphurised, selenised and/or tellurised form and the deposit having a specific surface area of more than 1 m2/g; a method for preparing such an electrode; and a method for oxygenising water with dioxygen involving such an electrode.Type: GrantFiled: March 31, 2017Date of Patent: May 30, 2023Assignees: Paris Sciences et Lettres, Centre National de la Recherche Scientifique (CNRS), Sorbonne UniversiteInventors: Marc Fontecave, Victor Mougel, Ngoc Huan Tran
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Publication number: 20230054300Abstract: The present application relates to a double-stranded DNA molecule comprising a first double-stranded DNA molecule (1) connected to a second double-stranded DNA molecule (2) by at least one covalent bond which is not a phosphodiester, phosphorothioate, phosphoramidate or phosphorodiamidate bond, preferably by a tether, said tether preferably being a double-stranded DNA molecule.Type: ApplicationFiled: December 21, 2018Publication date: February 23, 2023Applicants: PARIS SCIENCES ET LETTRES - QUARTIER LATIN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NORMALE SUPERIEURE, UNIVERSITÉ DE PARISInventors: Térence STRICK, Charlie GOSSE, Dorota KOSTRZ, Jinglong WANG, Marc NADAL
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Publication number: 20230032722Abstract: A full-field optical coherence tomography imaging method, FFOCT, using a system comprising an FFOCT device and a sample, the sample comprising a layer of interest to be imaged, the FFOCT device comprising an incoherent light source, an imager, a beam splitter defining a sample arm and a reference arm, the method comprising-generating sample light containing interest light originating from the layer of interest and reference light traveling from the reference arm, —acquiring an image from reference light and sample light combined in the beam splitter; wherein at least one of the sample arm and the reference arm comprises an optical curvature compensator that modifies a transverse variation distribution of an optical path length to match the transverse variation distributions of the optical path lengths travelled by the reference light and the interest light incident on the imager.Type: ApplicationFiled: December 18, 2020Publication date: February 2, 2023Applicants: Paris Sciences et Lettres, Centre National de la Recherche Scientifique (CNRS), Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De ParisInventors: Viacheslav Mazlin, Pedro Francisco Baracal De Mece, Albert Claude Boccara
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Patent number: 11542583Abstract: The invention relates to the use of a ternary Titanium-Zirconium-Oxygen (Ti—Zr—O) alloy, characterized in that it comprises from 83% to 95.15 mass % of titanium, from 4.5% to 15 mass % of zirconium and from 0.35% to 2 mass % of oxygen, with said alloy being capable of forming a single-phase material consisting of a stable and homogeneous ? solid solution of Hexagonal Close Packed (HCP) structure at room temperature in the medical, transport or energy fields.Type: GrantFiled: March 10, 2021Date of Patent: January 3, 2023Assignees: Paris Sciences et Lettres, Centre National de la Recherche Scientifique (CNRS), Biotech DentalInventors: Frédéric Prima, Stéphanie Delannoy
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Patent number: 11541359Abstract: The invention relates to the extraction of organic compounds from mixtures of said compounds with water, using a nanoporous carbon membrane. The invention can be used in any field where it is desired to separate an organic compound of interest from water, such as the drying of alcohols or alkanes.Type: GrantFiled: March 27, 2017Date of Patent: January 3, 2023Assignees: Paris Sciences et Lettres, Université Paris Cité, Centre National De La Recherche Scientifique (CNRS), Sorbonne UniversiteInventors: Lyderic Bocquet, Alessandro Siria, Benoit Laborie, Hiroaki Yoshida, Simon Gravelle
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Publication number: 20220356520Abstract: The present invention relates to a digital multiplex method for detecting and/or quantifying multiple target biomolecules in a sample, said biomolecules being selected from DNA, RNA, and proteins. The present invention further relates to different applications of the digital multiplex method and to a kit.Type: ApplicationFiled: May 27, 2020Publication date: November 10, 2022Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, PARIS SCIENCES ET LETTRES, UNIVERSITE DE PARISInventors: Guillaume GINES, Yannick RONDELEZ, Thomas JET, Valérie TALY
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Publication number: 20220333177Abstract: The present invention relates to a digital method for detecting and/or quantifying at least one target biomolecules in a sample, said biomolecules being selected from DNA, RNA, and proteins based on isothermal amplification. The present invention further relates to different applications of the digital method and to a kit.Type: ApplicationFiled: May 27, 2020Publication date: October 20, 2022Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, PARIS SCIENCES ET LETTRES, UNIVERSITE DE PARISInventors: Yannick RONDELEZ, Guillaume GINES, Roberta LIMA DE CASTRO MENEZES, Valérie TALY
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Publication number: 20220257671Abstract: Recombinant, alive and metabolically active bacteria including a heterologous prokaryotic biomineralized ferritin. In particular, the inventors have shown that naturally non-magnetic Escherichia coli may be engineered to become magnetic by the expression and the biomineralization of the ferritin of Pyrococcus furiosus. Moreover, the inventors have shown that a fixed number of magnetic E. coli strains keep their magnetic properties through cell division by asymmetrical division. The inventors have also shown that magnetic bacteria according to the invention may be of use in both non-therapeutic and therapeutic uses, such as, e.g., the biosensing of target substance, the depollution of complex environments, the display of antibodies, nanobodies and antigens, the delivery of therapeutic substance to target cells, the targeting and infection of target cells.Type: ApplicationFiled: July 24, 2020Publication date: August 18, 2022Applicants: PARIS SCIENCES ET LETTRES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE, MUSÉUM NATIONAL D'HISTOIRE NATURELLE (MNHN)Inventors: Zoher GUEROUI, Mary AUBRY, Wei-An WANG, François GUYOT
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Publication number: 20220236301Abstract: The present invention relates to an atomic force microscope for evaluating a surface of a sample, comprising a sample holder, having a first zone suitable for receiving the sample mounted in a stationary manner, a probe having a tip able to be positioned facing the surface of the sample, the microscope being configured to allow an adjustment of a position of the tip relative to the surface, and a support, the sample holder having at least one second zone, separate from the first zone and stationary relative to the support, the sample holder being deformable so as to allow a relative movement of the first zone with respect to the second zone, and the microscope comprising a detector able to detect a movement of the first zone relative to the second zone.Type: ApplicationFiled: July 16, 2020Publication date: July 28, 2022Applicants: Paris Sciences et Lettres, Centre National de la Recherche Scientifique (CNRS), Sorbonne Universite, Université de ParisInventors: Antoine Niguès, Alessandro Siria
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Patent number: 11388808Abstract: The present invention relates to a plasma reactor and more specifically to an plasma microreactor comprising a support, made at least partially of a dielectric material, the support comprising a gas inlet, a liquid inlet, at least a fluid outlet, a liquid microchannel in the support, a gas channel, at least a ground electrode, at least a high voltage electrode, separated from the gas channel by the dielectric material of the support, wherein said ground electrode and said high voltage electrode are arranged on opposite sides of the gas channel so as to be able to create an electric field inside the gas channel, wherein the liquid microchannel and the gas channel are contiguous and at least an opening is arranged between the liquid microchannel and the gas channel so as to form a fluid channel and to cause the liquid flow contact the gas flow and wherein the liquid flow is retained within the liquid microchannel by capillarity action.Type: GrantFiled: February 28, 2019Date of Patent: July 12, 2022Assignees: Paris Sciences et Lettres, Centre National de la Recherche Scientifique (CNRS), Sorbonne Universite, Ecole Nationale Supérieure de Chimie de ParisInventors: Julien Wengler, Stéphanie Ognier, Safwan Al Ayoubi, Michael Tatoulian
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Publication number: 20220169682Abstract: A complementation system including two fragments of photoactive yellow protein (PYP), or truncated fragments thereof, and its use with a fluorogenic hydroxybenzylidene rhodanine (HBR) analog for detecting interactions between biological molecules of interest, in particular between proteins of interest. Especially, a complementation system including a first PYP fragment having an amino acid sequence having at least about 70% identity with the amino acid sequence of SEQ ID NO: 23, or a truncated fragment thereof including at least 89 consecutive amino acids from the C-terminal end of the amino acid sequence; and a second PYP fragment having an amino acid sequence having at least about 70% identity with the amino acid sequence of SEQ ID NO: 34, or a truncated fragment thereof including at least 8 consecutive amino acids of the amino acid sequence, preferably 8 consecutive amino acids from the N-terminal end of the amino acid sequence.Type: ApplicationFiled: April 3, 2020Publication date: June 2, 2022Applicants: PARIS SCIENCES ET LETTRES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITÉInventors: Arnaud GAUTIER, Alison TEBO
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Publication number: 20220127736Abstract: The present invention relates to an electrolysis device comprising an anode and a cathode, wherein the anode and the cathode each are an electrode comprising an electrically conductive support of which at least a part of the surface is covered by a metal deposit of copper, wherein the surface of the metal deposit is in an oxidized, sulfurated, selenated and/or tellurized form and the metal deposit has a specific surface area greater than or equal to 1 m2/g. The present invention relates also to a method for reducing CO2 into hydrocarbons using an electrolysis device according to the invention. The method according to the invention comprises: a) providing an electrolysis device according to the invention; b) exposing the cathode of said electrolysis device to a CO2-containing aqueous catholyte solution; c) exposing the anode of said electrolysis device to an aqueous anolyte solution; and d) applying an electrical current between the anode and the cathode in order to reduce the carbon dioxide into hydrocarbons.Type: ApplicationFiled: November 21, 2019Publication date: April 28, 2022Applicants: Paris Sciences et Lettres - Quartier Latin, College de France, Centre National de la Recherche Scientifique (CNRS), Sorbonne Universite, College de FranceInventors: Marc Fontecave, Victor Mougel, Huan Tran Ngoc, Daniel Alves Dalla Corte, Sarah Lamaison, Lukas Lutz
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Patent number: 11253835Abstract: The present invention relates to a microfluidic or millifluidic device (1) comprising: —a support (2) made at least partially of a dielectric material, the support (2) comprising a first inlet (21a) adapted to be connected to a first reservoir containing gas, a second inlet (21b) adapted to be connected to a second reservoir containing liquid, an outlet (22) adapted to be connected to a receiver container containing gas and/or liquid, and a main microchannel or millichannel (3) present in the dielectric material allowing the liquid and the gas to flow from the inlets towards the outlet, —one or several ground electrode(s) (4) embedded in said dielectric material and extending along the main microchannel or millichannel (3), and —one or several high-voltage electrode(s) (5) embedded in said dielectric material and extending along the main microchannel or millichannel (3), wherein the high-voltage electrode(s) (5) and the ground electrode(s) (4) are located on opposite sides of the main microchannel or millichaType: GrantFiled: December 9, 2016Date of Patent: February 22, 2022Assignees: Paris Sciences et Lettres, Centre National de la Recherche Scientifique (CNRS), Sorbonne UniversiteInventors: Michael Tatoulian, Stéphanie Ognier, Mengxue Zhang
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Publication number: 20220040664Abstract: The present invention concerns a reactor for the conversion of carbon dioxide or carbon monoxide into hydrocarbon and/or alcohol comprising a support made from an electrically and thermally conductive material, forming the wall or walls of at least one longitudinal channel that passes through the support and also acting as the cathode of the reactor, at least one wire electrode forming an anode of the reactor, and extending within each longitudinal channel, and being arranged at a distance from the wall or walls of the longitudinal channel, each wire electrode optionally being covered with an electrically insulating layer along the part of the wire electrode extending within the longitudinal channel, a catalyst capable of catalysing a conversion reaction for the conversion of carbon dioxide or carbon monoxide into hydrocarbon and/or alcohol, the catalyst being situated between the wire electrode and the wall or walls of each longitudinal channel.Type: ApplicationFiled: December 20, 2019Publication date: February 10, 2022Applicants: Paris Sciences et Lettres, Centre National de la Recherche Scientifique (CNRS), Sorbonne Universite, Ecole Nationale Superieure de Chimie de Paris, Univ Paris XIII Paris-Nord VilletaneuseInventors: Vincent Piepiora, Stéphanie Ognier, Simeon Cavadias, Xavier Duten, Michael Tatoulian, Maria Elena Galvez-Parruca, Patrick Da Costa
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Publication number: 20210345873Abstract: According to one aspect, the invention relates to a system (101) for in vivo, full-field interference microscopy imaging of a scattering three-dimensional sample.Type: ApplicationFiled: September 27, 2019Publication date: November 11, 2021Applicants: PARIS SCIENCES ET LETTRES - QUARTIER LATIN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARISInventors: Viacheslav Mazlin, Peng Xiao, Mathias Fink, Albert Claude Boccara
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Patent number: 11162951Abstract: Fluorescent labeling of proteins. In particular, membrane-impermeant fluorogenic chromophores being capable of binding reversibly a functional derivative of a Photoactive Yellow Protein (PYP), or a functional fragment thereof, for fluorescently labeling biological molecules of interest, preferably proteins of interest. Especially, 4-hydroxybenzylidene-rhodanine (HBR) analogs of formula (II) as membrane-impermeant fluorogenic chromophores.Type: GrantFiled: May 18, 2018Date of Patent: November 2, 2021Assignees: PARIS SCIENCES ET LETTRES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, SORBONNE UNIVERSITEInventors: Arnaud Gautier, Ludovic Jullien, Chenge Li, Franck Perez
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Publication number: 20210290142Abstract: The invention concerns a method for calibrating a system for real-time measurement of the activity of a cognitive function of a test subject, the method comprising the successive steps of: acquiring electrical signals representative of a neural activity of a test subject; calculating values of markers of the cognitive function activity; generating a plurality of copies of calculated values of markers and adding noise to the generated copies; and, constructing a classifier by machine learning, based on the calculated marker values and noisy copies, the classifier being suitable for measuring the activity of the cognitive function of the test subject by calculating a probability that an electrical signal representative of the neural activity of the test subject results from a predetermined activity state of the cognitive function of the test subject.Type: ApplicationFiled: November 21, 2018Publication date: September 23, 2021Applicants: Paris Sciences Et Lettres - Quartier Latin, Centre National de la Recherche Scientifique (CNRS), Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris, Sorbonne UniversiteInventors: François Vialatte, Aldo Mora-Sanchez, Gérard Dreyfus, Antoine Gaume, Alfredo Aram Pulini