Abstract: Engineered proteins, polynucleotides encoding such proteins, and methods of use thereof are provided, which engineered proteins enhance the sensitivity of a cell to IL-2.
Type:
Grant
Filed:
December 5, 2018
Date of Patent:
October 10, 2023
Assignees:
The Board of Trustees of the Leland Stanford Junior University, Parker Institute for Cancer Immunotherapy
Inventors:
Kenan Christopher Garcia, Sean Parker, Jonathan Sockolosky, Michael Hollander