Abstract: A protective probe cover set for a medical probe designed to be inserted in an endocavity or used interoperatively in an incision of a human or an animal body, comprises a probe cover and a sheath-like outer wrapper. The probe cover consists of flat film material and comprises a mouth for inserting the probe. The outer wrapper consists of two plies being joined along their longitudinal edges. The outer wrapper sheaths at least the length of the cover designed to be inserted in said endocavity. The film material is non sensitizing. Preferably, the probe cover is at least partly filled with a gel which is an excellent transmitter for ultrasound waves and can have lubricating properties, for ease of insertion of the probe into the probe cover, while on the other hand, deterimental effects of air bubbles or the like enclosed between the probe cover and the probe itself are avoided.