Patents Assigned to Pasteur Merieux
  • Method for purifying factor VIII and preparations obtained
    Patent number: 5371195
    Abstract: In the method for purifying factor VIII from cryoprecipitate, which is dissolved and then treated with alumina gel, the extract is diluted to a protein concentration not exceeding approximately 5 g/l and subjected to viral inactivation with solvent/detergent, the inactivated extract containing the solvent/detergent is then subjected to chromatography on a weak anion exchange column which is hydrophilic in nature and factor VIII is then eluted with a dissociating buffer.
    Type: Grant
    Filed: September 23, 1992
    Date of Patent: December 6, 1994
    Assignee: Pasteur Merieux
    Inventors: Michel Grandgeorge, Charles Lutsch