Abstract: Methods for the treatment of systemic mast cell related disorders treatable with mast cell stabilizers, including mast cell related disorders, are provided.
Type:
Application
Filed:
August 5, 2016
Publication date:
August 16, 2018
Applicant:
Patara Pharma, LLC
Inventors:
William Gerhart, Pravin Soni, Ahmet Tutuncu
Abstract: The disclosure provides a method of treating chronic cough in a subject having idiopathic pulmonary fibrosis (IPF) comprising administering to the subject a pharmaceutical composition comprising from about 2% by weight to about 6% by weight of cromolyn sodium and an ionic osmotic agent with a nebulizer.
Type:
Application
Filed:
February 2, 2018
Publication date:
July 12, 2018
Applicant:
Patara Pharma, LLC
Inventors:
William Gerhart, Ahmet Tutuncu, Pravin Soni
Abstract: The disclosure provides a method of treating chronic cough in a subject having idiopathic pulmonary fibrosis (IPF) comprising administering to the subject a pharmaceutical composition comprising from about 2% by weight to about 6% by weight of cromolyn sodium and an ionic osmotic agent with a nebulizer.
Type:
Application
Filed:
February 2, 2018
Publication date:
July 12, 2018
Applicant:
Patara Pharma, LLC
Inventors:
William Gerhart, Ahmet Tutuncu, Pravin Soni
Abstract: Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders, are provided. Some embodiments relate to dosage forms. Dosage forms can include an aqueous pharmaceutical composition containing (i) from about 2% to about 6% by weight of cromolyn sodium, and (ii) an osmolarity adjusting agent consisting of (A) between about 0.1% to about 0.5% by weight of sodium chloride, inclusive of the endpoints, and (B) optionally salts of EDTA; and an inhalation device that forms an aerosol of said pharmaceutical composition, said aerosol exhibiting a respirable fraction of said pharmaceutical composition (<5 ?m) as measured by USP <1601> of at least about 60%, are provided.
Type:
Grant
Filed:
August 9, 2016
Date of Patent:
July 18, 2017
Assignee:
Patara Pharma, LLC
Inventors:
William Gerhart, Manfred Keller, Ahmet Tutuncu, Pravin Soni