Abstract: Example implementations relate to an electronic system providing thermal management of a removable device when connected to a host device of the electronic system including a receptacle, and a heat transfer device having first and second portions. The host device has a cooling component. The removable device having a heat spreader, is detachably coupled to the host device. The receptacle having spring fingers, is coupled to one of the cooling component or the heat spreader. The first portion is coupled to one of the cooling component or the heat spreader, and the second portion is protruded outwards. When the removable device is connected to the host device, the second portion extends through the receptacle such that the spring fingers establish direct thermal interface with the second portion to allow waste-heat to transfer between the heat transfer device and one of the cooling component or the heat spreader via the receptacle.

Abstract: A method and apparatus for use in a trusted network environment together or separately employ an implicit attestation that a requesting computing resource is in a trusted state before access to a network resource is granted. The method includes: verifying that a requesting computing resource is in a trusted state; accessing the private key using the released key authorization value; and creating a digital signature for the requesting device from the accessed private key. The apparatus may implement the method.

Abstract: A process in which a catalytic cracking unit is operated to crack a hydrocarbon feedstock in a manner to enhance light olefin yields. The accompanying benzene-containing naphtha product stream is further processed through a benzene selective membrane to provide a low content benzene stream. Refiners frequently operate their cracking units to optimize light olefin yields, e.g. propylene, in response to needs in the petrochemical industry, and it has been discovered that units operated in this manner frequently produce naphtha containing increased amounts of benzene. The method of this invention therefore allows one to operate the unit when it is desired to optimize light olefin yields, yet at the same time produce a naphtha yield having a low benzene content. The invention is particularly useful when the cracking unit utilizes pentasil zeolites at increased concentrations to enhance light olefins yield.

Abstract: The present invention relates to novel heterocyclic amide compounds of Formula I: as disclosed herein or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are compositions comprising said compounds, and methods for using said compounds for treating or preventing a proliferative disease, an anti-proliferative disorder, inflammation, arthritis, a neurological or neurodegenerative disease, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease or a fungal disease.

Abstract: The present invention discloses novel compounds, which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

Abstract: A method for identifying real-time traffic hop by hop in an Internet network including a sender, a receiver, and routers in the network is provided. The method comprises steps of registering source port number and/or destination port number of the UDP respectively for RTP, RTCP and RTSP with the Internet Assigned Numbers Authority (IANA) under the Internet Engineering Task Force (IETF) arrangement, then in one aspect, adding in the UDP header a Session ID field for identifying the session. The method can be used to identify the frames of the Real-time Transport Protocol (RTP) hop by hop during the packet's transmission, and to provide priority for real-time traffic transport so as to provide a QoS guarantee for real-time traffic even in the case of dramatically increasing network traffic.

Abstract: The present application is directed to a method for performing a bisulfite reaction to determine methylation positions in a nucleic acid, i.e. methylated and non-methylated cytosines. In this method, the nucleic acid is bisulfite treated and is bound to a solid phase when an alkaline solution is added for desulfonation and elution of the nucleic acid from the solid phase. The nucleic acid can be amplified in an additional step. The solid phase is preferably a material comprising glass or silica, more preferably a glass fleece, glass membrane or a magnetic glass particle. Further, several uses of the alkaline solution for bisulfite treatment are disclosed and a kit containing a bisulfite reagent, a solid phase and an alkaline solution.

Abstract: Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein

Abstract: Disclosed are compounds Formula I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.

Abstract: This invention provides a compound, or its possible salt, having the formula, wherein: Re and ?Re are OH, optionally independently etherified or esterified; Z is —CH2CH2— or —C(R4,R5)—, wherein R4 and R5 are independently H, (1C-2C)alkyl or form together a spiro(3C-5C)cycloalkyl; R1 is H, halogen, CF3 , or (1C-4C)alkyl; R2 and R3 are independently H, halogen, —CF3, —OCF3, (1C-8C)alkyl, hydroxy, (1C-8C)alkyloxy, aryloxy, aryl(1C-8C)alkyl, halo(1C-8C)alkyl, —O(CH2)mX, wherein X is halogen or phenyl and m=2-4; —O(CH2)mNRaRb, —S(CH2)mNRaRb or —(CH2)mNRaRb, wherein m=2-4 and wherein Ra, Rb are independently (1C-8C)alkyl, (2C-8C)alkenyl, (2C-8C)alkynyl, or aryl, which alkyl, alkenyl and aryl can optionally be substituted with halogen, —CF3, —OCF3, —CN, —NO2, —OH, (1C-8C)alkoxy, aryloxy, carboxyl, (1C-8C)alkylthio, carboxylate, (1C-8C)alkyl, aryl, aryl(1C-8C)alkyl or halo(1C-8C)alkyl; or Ra and Rb form a 3-8 membered ring structure, optionally substituted with halogen, —CF3, —OCF3, —CN, —NO2, hydroxy, hydroxy(1

Abstract: The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Preferred tertiary-heteroalkylamine compounds are substituted N,N-disubstituted non-fused heterocyclo amines.

Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.

Abstract: Five independent transgenic founder lines were created which have all developed cardiac hypertrophy and heart failure. The line with the most severe phenotype was analyzed in detail. Transgenic cardiac 11&bgr;HSD2 mRNA expression is increased 4,000 fold over non-transgenic mice and the expressed enzyme was found to possess catalytic activity. At five months of age transgenic mice had developed severe myocardial hypertrophy in the absence of an increase in blood pressure. Interstitial fibrosis in the left ventricle of transgenic mice was revealed by picrosirius red staining. The hearts of the mice were severely dilated and cardiomyocyte size was increased.

Abstract: The present invention provides methods for the treatment or prophylaxis of one or more aldosterone-mediated pathogenic effects in a subject suffering from or susceptible to the pathogenic effect or effects wherein the subject has one or more conditions selected from the group consisting of a sub-normal endogenous aldosterone level, salt sensitivity and an elevated dietary sodium intake. The methods comprise administering to the subject a therapeutically-effective amount of one or more aldosterone antagonists.

Abstract: Compounds of the formula I R—Q—X  I, in which R, Q, and X are as defined herein, can be used as integrin inhibitors. In particular, compounds of formula I are suitable for the treatment of disorders caused by implants, defects, inflammations and of osteolytic disorders such as osteoporosis, thrombosis, cardiac infarct and arteriosclerosis. These compounds are also suitable for the acceleration and reinforcement of the integration process of implants and biocompatible surfaces into tissue.

Abstract: A class of compounds is described which can be used for the treatment of viral infections.

Abstract: An apparatus which is capable of storing a plurality of printing plates includes a sleeve having one open end which receives the printing plates and a handle connected to the sleeve. The sleeve comprises two mutually-opposed surfaces which enclose all but one edge of each received printing plate. The edges are enclosed such that all of the edges, but one, are unexposed external to the apparatus and such that the one edge which is exposed is only partially exposed. The sleeve also includes a plurality of stiffening members therein for maintaining substantial rigidity thereof.

Abstract: A system for developing photographic film which is ecologically friendly includes a tray holding a pair of film cassettes. One cassette includes negative film sheets which is inserted into a camera where the negative sheets are exposed. The exposed sheets are delivered to a developing apparatus. A second cassette from the tray includes positive film sheets and it is delivered to the same developing apparatus. The empty tray is mounted on the developing apparatus. Each positive film sheet includes a rupturable pod of developer liquid for spreading between mated positive and negative film sheets. Exposed negative sheets and positive sheets are mated and the pod ruptured to spread liquid between the two as the mated sheets move in a first path into an imbibition chamber. A pick at the exit end of the imbibition chamber strips the evacuated pod, negative film sheet and residual developer liquid from the positive sheet and delivers them to the face of a ram.

Abstract: Substituted anthrasteroid derivatives represented by the following formula: ##STR1## wherein R is hydrogen or lower alkyl; X is hydrogen, lower alkyl, halogen, hydroxy, hydroxymethyl, or halomethyl; Y is C.dbd.O, CH.about.OR', or OH C R", wherein R' is hydrogen, lower alkyl, cycloalkyl which may have an unsaturated bond or a substituent, or aliphatic lower acyl which may have carboxy or its lower alkyl ester at the terminal; R" is lower alkyl or lower alkynyl; the dotted line indicates the presence or absence of double bond; and the wavy line indicates .alpha. or .beta. configuration; or ketal derivatives thereof being effective against androgen-dependent diseases e.g., prostatic hypertrophy, prostatic cancer.

Abstract: There is disclosed a method of finishing or smoothing the surface of an optical start rod through the use of plasma heat in an atmosphere which prevents contamination of the rod by residual water. Also there is disclosed a method of fabricating an optical waveguide wherein the start rod has deposited thereon silica soot and which is subsequently consolidated by a plasma.