Abstract: Amorphous dispersion granules comprising an amorphous solid solution of an active pharmaceutical ingredient and a dispersing polymer, and deposited thereon a substrate comprising at least one first tableting agent, as well as oral dosage forms comprising the amorphous dispersion granules of the invention, including pharmaceutically acceptable tablets comprising the amorphous dispersion granules of the invention, and methods of preparing amorphous dispersion granules and pharmaceutically acceptable tablets manufactured therefrom.
Type:
Application
Filed:
November 14, 2016
Publication date:
December 6, 2018
Applicant:
PATHEON DEVELOPMENT SERVICES INC.
Inventors:
Sanjay Konagurthu, Thomas REYNOLDS, Marshall CREW