Abstract: The present invention provides compositions, kits, and method for determining the levels of expression of human polyoma or papillomavirus species and RNA transcripts. These levels can be used for the prognosis of risk of developing virally-induced cancers. The ratio (R) between early and late transcripts is indicative of HPV infections associated with higher risk of developing genital neoplasia and cancer.
Type:
Grant
Filed:
July 7, 2015
Date of Patent:
October 20, 2020
Assignees:
INSTITUT PASTEUR, ECOLE NATIONALE VETERINAIRE D'ALFORT, PATHQUEST, L'ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
Inventors:
Marc Eloit, Nicolas Torno, Jean Deregnaucourt, Marion Mouton, Isabelle Heard, Philippe Perot