Abstract: Disclosed is a method of treating disorders which have prominent symptoms of behavioral disinhibition (e.g., Attention-Deficit Hyperactivity Disorder, Conduct Disorder, Oppositional Defiant Disorder, Tourette's Syndrome, Lesch-Nyhan Syndrome, or the disinhibitory symptoms accompanying Post-traumatic Stress Disorder or dementia) in a primate with minimal sedative side effects by administering thereto a therapeutically effective amount of guanfacine.
Type:
Grant
Filed:
September 21, 1995
Date of Patent:
December 29, 1998
Assignees:
Amy F. T. Arnsten, Patricia Goldman-Rakic, Robert H. Hunt
Inventors:
Amy F. T. Arnsten, Patricia S. Goldman-Rakic, Robert H. Hunt