Patents Assigned to Patrys Limited
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Patent number: 9783599Abstract: The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject.Type: GrantFiled: March 14, 2014Date of Patent: October 10, 2017Assignee: Patrys LimitedInventors: Heinz Peter Vollmers, Stephanie Ute Brandlein, Andreas Thalheimer, Leodevico L. Ilag, Barbara E. Power, Lishanthi Udabage, Frank Hensel, Frank Schoenen, Arndt-Rene Kelter, Christopher Garth Hosking
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Patent number: 9273125Abstract: Purified polypeptide is proposed, the amino acid sequence of which is essentially identical to the amino acid sequence of SEQ ID NO:1 and SEQ ID NO:3, the polypeptide binding low density lipoproteins (LDL) and/or oxidized LDL (oxLDL), in particular LDL cholesterol and/or oxidized LDL cholesterol (oxLDL cholesterol). The invention includes the use of the polypeptide in combination with conventional adjuvants and/or carrier substances for producing a drug having a fat-reducing effect and for producing drugs for treating renal diseases.Type: GrantFiled: February 27, 2012Date of Patent: March 1, 2016Assignee: Patrys LimitedInventor: Heinz Peter Vollmers
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Patent number: 9265817Abstract: The present disclosure relates generally to epitopes of an antibody known as PAT-LM1, and methods for using said epitopes.Type: GrantFiled: October 29, 2012Date of Patent: February 23, 2016Assignee: Patrys LimitedInventors: Arndt-Rene Kelter, Frank Hensel, Leodevico L. Ilag, Barbara Power, Christopher Garth Hosking
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Publication number: 20150071931Abstract: The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject.Type: ApplicationFiled: March 14, 2014Publication date: March 12, 2015Applicant: Patrys LimitedInventors: Heinz Peter Vollmers, Stephanie Ute Brandlein, Andreas Thalheimer, Leodevico L. Ilag, Barbara E. Power, Lishanthi Udabage, Frank Hensel, Frank Schoenen, Arndt-Rene Kelter, Christopher Garth Hosking
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Patent number: 8741296Abstract: The present invention features a polypeptide, such as an antibody produced by the hybridoma SAM-6 and its use in the treatment and diagnosis of neoplasms.Type: GrantFiled: March 23, 2012Date of Patent: June 3, 2014Assignee: Patrys LimitedInventors: Heinz Peter Vollmers, Hans-Konrad Müller-Hermelink
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Patent number: 8562995Abstract: The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms.Type: GrantFiled: May 19, 2011Date of Patent: October 22, 2013Assignee: Patrys LimitedInventors: Hans-Konrad Müeller-Hermelink, Heinz Peter Vollmers
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Publication number: 20130101588Abstract: The invention provides polypeptide, nucleic acid and other compositions. Polypeptide, nucleic acid and other compositions are useful in treatment and diagnostic methods. One treatment method includes inhibiting growth or proliferation of hyperproliferative cells or inducing regression of hyperproliferative cells, such as cells of a cellular hyperproliferative disorder, or reducing levels of LDL or oxLDL.Type: ApplicationFiled: August 2, 2010Publication date: April 25, 2013Applicant: PATRYS LIMITEDInventor: Heinz Peter Vollmers
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Publication number: 20130072664Abstract: Purified polypeptide is proposed, the amino acid sequence of which is essentially identical to the amino acid sequence of SEQ ID NO:1 and SEQ ID NO:3, the polypeptide binding low density lipoproteins (LDL) and/or oxidized LDL (oxLDL), in particular LDL cholesterol and/or oxidized LDL cholesterol (oxLDL cholesterol). The invention includes the use of the polypeptide in combination with conventional adjuvants and/or carrier substances for producing a drug having a fat-reducing effect and for producing drugs for treating renal diseases.Type: ApplicationFiled: February 27, 2012Publication date: March 21, 2013Applicant: PATRYS LIMITEDInventor: HEINZ PETER VOLLMERS
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Publication number: 20130039849Abstract: The present invention features a polypeptide, such as an antibody produced by the hybridoma SAM-6 and its use in the treatment and diagnosis of neoplasms.Type: ApplicationFiled: March 23, 2012Publication date: February 14, 2013Applicant: PATRYS LIMITEDInventors: HEINZ VOLLMERS, Hans-Konrad Müller-Hermelink
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Patent number: 8163552Abstract: A purified polypeptide that binds to neoplastic cells, which may be an antibody, is produced by the hybridoma SAM-6, a method for its production and use in the treatment and diagnosis of neoplasms.Type: GrantFiled: November 12, 2004Date of Patent: April 24, 2012Assignee: Patrys LimitedInventors: Heinz Vollmers, Hans-Konrad Müller-Hermelink
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Patent number: 8124080Abstract: A purified polypeptide having an amino acid sequence that is substantial identical with the amino acid sequence of SEQ ID NO:1, SEQ ID NO:3, or both, in which the polypeptide binds low density lipoproteins (LDL) or oxidized LDL (oxLDL), or both, and particularly binds well to LDL cholesterol and oxidized LDL cholesterol. The polypeptide may be used in combination with conventional adjuvants or carrier substances for producing a drug having a fat-reducing effect and for producing drugs for aiding in the treatment of renal diseases.Type: GrantFiled: November 12, 2004Date of Patent: February 28, 2012Assignee: Patrys LimitedInventor: Heinz Peter Vollmers
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Publication number: 20110287021Abstract: The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms.Type: ApplicationFiled: May 19, 2011Publication date: November 24, 2011Applicant: PATRYS LIMITEDInventors: Hans-Konrad Mueller-Hermelink, Heinz Peter Vollmers
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Publication number: 20110207917Abstract: The invention provides polypeptide, nucleic acid and other compositions. Polypeptide, nucleic acid and other compositions are useful in treatment and diagnostic methods. One treatment method includes inhibiting growth or proliferation of hyperproliferative cells or inducing regression of hyperproliferative cells, such as cells of a cellular hyperproliferative disorder, or reducing levels of LDL or oxLDL.Type: ApplicationFiled: February 9, 2010Publication date: August 25, 2011Applicant: PATRYS LIMITEDInventors: Leodevico I. Ilag, Barbara Power, Lishanthi Udabage
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Patent number: 7947812Abstract: The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms.Type: GrantFiled: March 15, 2004Date of Patent: May 24, 2011Assignee: Patrys LimitedInventors: Hans-Konrad Mueller-Hermelink, Heinz Peter Vollmers
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Publication number: 20110076763Abstract: The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms.Type: ApplicationFiled: August 17, 2010Publication date: March 31, 2011Applicant: PATRYS LIMITEDInventors: HEINZ PETER VOLLMERS, Hans Konrad Mueller-Hermelink
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Publication number: 20100322936Abstract: The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject.Type: ApplicationFiled: June 15, 2009Publication date: December 23, 2010Applicant: PATRYS LIMITEDInventors: HEINZ PETER VOLLMERS, STEPHANIE UTE BRANDLEIN, ANDREAS THALHEIMER, LEODEVICO L. ILAG, BARBARA E. POWER, LISHANTHI UDABAGE, FRANK HENSEL, FRANK SCHOENEN, ARNDT-RENE KELTER, CHRISTOPHER GARTH HOSKING
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Publication number: 20100317826Abstract: The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms.Type: ApplicationFiled: June 7, 2010Publication date: December 16, 2010Applicant: PATRYS LIMITEDInventors: HANS-KONRAD MUELLER-HERMELINK, Heinz Vollmers
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Patent number: 7772372Abstract: The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms.Type: GrantFiled: July 2, 2003Date of Patent: August 10, 2010Assignee: Patrys LimitedInventors: Hans-Konrad Mueller-Hermelink, Heinz Vollmers
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Patent number: 7741444Abstract: The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms.Type: GrantFiled: August 14, 2007Date of Patent: June 22, 2010Assignee: Patrys LimitedInventors: Hans-Konrad Mueller-Hermelink, Heinz Peter Vollmers
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Publication number: 20090291083Abstract: The invention provides antibodies, functional fragments, modified and variant forms, antibody targets, nucleic acid and other compositions. Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment, diagnostic and vaccination methods. One treatment method includes inhibiting growth or proliferation of proliferating cells, such as hyperproliferative cells or inducing regression of hyperproliferative cells, such as cells of a cellular hyperproliferative disorder.Type: ApplicationFiled: January 7, 2009Publication date: November 26, 2009Applicant: PATRYS LIMITEDInventors: Heinz Peter Vollmers, Stephanie ute Brandlein, Leodevico L. Ilag, Barbara Power, Frank Hensel