Patents Assigned to PCT Therapeutics, Inc.
  • Compounds for Nonsense Suppression, and Methods for Their Use
    Publication number: 20090253699
    Abstract: The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.
    Type: Application
    Filed: October 13, 2005
    Publication date: October 8, 2009
    Applicant: PCT Therapeutics, Inc.
    Inventors: Neil G. Almstead, Guangming Chen, Gary M. Karp, Ellen Welch, Richard Wilde, Jeffrey A. Campbell
  • Carboline Derivatives Useful in the Inhibition of Angiogenesis
    Publication number: 20070281962
    Abstract: In accordance with the present invention, compounds that inhibit the expression of VEGF post-transcriptionally have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the inhibition of VEGF production, in the inhibition of angiogenesis, and/or in the treatment of cancer, diabetic retinopathy or exudative macular degeneration are provided. In another aspect of the invention, methods are provided for the inhibition of VEGF production, the inhibition of angiogenesis, and/or the treatment of cancer, diabetic retinopathy or exudative macular degeneration using the compounds of the invention.
    Type: Application
    Filed: March 15, 2005
    Publication date: December 6, 2007
    Applicant: PCT Therapeutics, Inc.
    Inventors: Young-Choon MOON, Liangxian CAO, Nadarajan TAMILARASU, Hongyan QI, Soongyu CHOI, William LENNOX, Donald CORSON, Seongwoo HWANG