Abstract: A tamper proof seal and container closure device including, in combination a seal ring and a closure, said seal ring being provided on its inner face with at least one recess and at least one stop, said closure being provided with at least one projection on the lower edge of the closure, said projection being adapted to fit within the recess of the seal so that when the combination seal ring and closure are fitted to a bottle neck the stop on the seal ring locks the seal ring, closure and bottle neck together. The combined seal ring and closure can be locked onto the bottle neck by the interaction between the stop on the seal and a complementary stop formed on the side of the base of the bottle neck.