Abstract: Disclosed are a root canal fluid filling device and method. The root canal fluid filling device includes a root canal filling device box, including an upper box body and a lower box body which are arranged in upper and lower partitions and detachable; a positive and negative pressure generating apparatus, arranged in the lower box body; an air pressure monitoring apparatus, arranged in the lower box body and connected to the positive and negative pressure generating apparatus; an air pressure recovery apparatus, arranged in the lower box body; an auxiliary positioning apparatus, including an auxiliary positioning crown which is respectively connected to the positive and negative pressure generating apparatus, the air pressure monitoring apparatus and the air pressure recovery apparatus and is to be sleeved outside and cemented to a tooth to be subjected to root canal therapy; a control display apparatus; and a power supply apparatus.

Abstract: A system and a method for predicting susceptibility of genus Klebsiella to amikacin are provided. The system includes a calculating unit containing a computer-readable storage medium stored with a computer program; the computer program is used to, when is executed by a processor, implement a calculation method for an Exp(?k) power value, and the calculation method for the Exp(?k) power value includes: step 1, calculating a k value according to formula I; and step 2, calculating the Exp(?k) power value with an Euler's constant e as a base and a ?k value as an exponential; and C1 to C5 are respectively copy numbers of an arr-2 gene, an acrB gene, an armA gene, an oqxB gene, and a rmtB gene in to-be-predicted Klebsiella strains. When the method and the system are adopted to predict the susceptibility of the genus Klebsiella to amikacin, an accuracy rate is about 98.8%.

Abstract: The present invention discloses a method for diagnosing congenital scoliosis of an individual, comprising: detecting whether a chromosome 16p11.2 region has a nucleotide sequence microdeletion of 0.6 Mb in length, or detecting whether a TBX6 gene has a frameshift mutation; and detecting a haplotype of two SNP sites of rs3809624-rs3809627 in the TBX6 gene located on another homologous chromosome. The diagnostic method of the present invention can be judged early in the congenital scoliosis and is suitable for clinical promotion. A method of treating congenital scoliosis is also provided.

Abstract: A preparation method of an anti-PD-1/PD-L1 monoclonal antibody (mAb)-induced autoimmune myocarditis model is provided, including: mediating a model with adeno-associated virus 9 (AAV9) to achieve the high expression of PDL1 in a myocardial tissue, and applying an anti-PD-1/PD-L1 mAb to the model with high PDL1 expression in the myocardial tissue for modeling. The present disclosure also provides use of an animal model prepared by the preparation method. The model prepared by the present disclosure truly simulates the pathogenesis and clinical course of autoimmune myocarditis in a patient administered with an anti-PD1/PD-L1 mAb, is close to a pathophysiological status of a clinical patient, has a high modeling rate, and can be dynamically monitored.

Abstract: A preparation method of an anti-PD-1/PD-L1 monoclonal antibody (mAb)-induced autoimmune myocarditis model is provided, including: mediating a model with adeno-associated virus 9 (AAV9) to achieve the high expression of PDL1 in a myocardial tissue, and applying an anti-PD-1/PD-L1 mAb to the model with high PDL1 expression in the myocardial tissue for modeling. The present disclosure also provides use of an animal model prepared by the preparation method. The model prepared by the present disclosure truly simulates the pathogenesis and clinical course of autoimmune myocarditis in a patient administered with an anti-PD1/PD-L1 mAb, is close to a pathophysiological status of a clinical patient, has a high modeling rate, and can be dynamically monitored.

Abstract: Disclosed is an artificial intelligence infrared thermal imaging bra system with breast disease detecting function. The system includes a side support, two chest support layers and two shoulder straps; the two shoulder straps are fixed at both ends of the side support, and the two chest support layers are symmetrically fixed between the two shoulder straps at the top of the side support; the two chest support layers are internally provided with sliding mechanisms that are adjustable according to different chests of users; a rotating mechanism for driving the sliding mechanisms to move is arranged between the two chest support layers at the top of the side support, and the rotating mechanism and the sliding mechanisms are in transmission connection; one end of the side support is fixed with a sub-buckle, and the other end of the side support is provided with a stretching mechanism.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: The disclosure provides an airway anomaly detection method and a ventilation device thereof. The method may include acquiring a ventilation parameter, where the ventilation parameter includes at least one of an airway pressure and airway flow; detecting, according to a change of the ventilation parameter, whether an airway anomaly event occurs; and when it is determined that the airway anomaly event occurs, outputting an airway anomaly event prompt.

Abstract: A ventilation detection method applied to a ventilation apparatus. The method may include monitoring respiratory parameters during mechanical ventilation of a patient by using a ventilation apparatus, the respiratory parameters at least comprising one of airway pressure and airway flow, and using changes in the respiratory parameters to identify whether man-machine counteraction or ventilation leakage has occurred.

Abstract: A ventilation trigger detection method performed by a ventilation device is disclosed. The method includes monitoring a ventilation parameter during mechanical ventilation for a user, the ventilation parameter including at least one of an airway pressure and an airway flow, and determining patient-ventilator synchrony during the ventilation according to a change in the ventilation parameter. Furthermore, this disclosure also relates to a ventilation trigger detection apparatus, a ventilation device, and a storage medium.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in the cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.