Patents Assigned to PellePharm, Inc.
  • Topical formulations for delivery of hedgehog inhibitor compounds and use thereof
    Patent number: 11413283
    Abstract: Compositions for topical administration of a hedgehog inhibitor compound are described. In one embodiment, the hedgehog inhibitor compound is patidegib and the topical composition comprises the compound in a solvent system of a monohydric primary alcohol and a polyol in a w/w ratio of between about 0.9-1.8. In another embodiment, the hedgehog inhibitor is itraconazole and the topical composition comprises the compound in a solvent system comprising a monohydric primary alcohol and an optionally lower alkyl end-capped oligomeric alkylene glycol in a w/w ratio of between about 0.8 and 2.6 and a fused bicyclic ether. Method of using the compositions are also described, where in one embodiment, the compositions are topically applied for treating or preventing basal cell carcinoma.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: August 16, 2022
    Assignee: PellePharm, Inc.
    Inventors: Marc Barry Brown, Cameron Robert Stevenson, Charles Rodney Greenaway Evans
  • Topical formulations for delivery of hedgehog inhibitor compounds and use thereof
    Patent number: 10695344
    Abstract: Compositions for topical administration of a hedgehog inhibitor compound are described. In one embodiment, the hedgehog inhibitor compound is patidegib and the topical composition comprises the compound in a solvent system of a monohydric primary alcohol and a polyol in a w/w ratio of between about 0.9-1.8. In another embodiment, the hedgehog inhibitor is itraconazole and the topical composition comprises the compound in a solvent system comprising a monohydric primary alcohol and an optionally lower alkyl end-capped oligomeric alkylene glycol in a w/w ratio of between about 0.8 and 2.6 and a fused bicyclic ether. Method of using the compositions are also described, where in one embodiment, the compositions are topically applied for treating or preventing basal cell carcinoma.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: June 30, 2020
    Assignee: PellePharm, Inc.
    Inventors: Marc Barry Brown, Cameron Robert Stevenson, Charles Rodney Greenaway Evans
  • Topical formulations for delivery of hedgehog inhibitor compounds and use thereof
    Patent number: 10369147
    Abstract: Compositions for topical administration of a hedgehog inhibitor compound are described. In one embodiment, the hedgehog inhibitor compound is patidegib and the topical composition comprises the compound in a solvent system of a monohydric primary alcohol and a polyol in a w/w ratio of between about 0.9-1.8. In another embodiment, the hedgehog inhibitor is itraconazole and the topical composition comprises the compound in a solvent system comprising a monohydric primary alcohol and an optionally lower alkyl end-capped oligomeric alkylene glycol in a w/w ratio of between about 0.8 and 2.6 and a fused bicyclic ether. Method of using the compositions are also described, where in one embodiment, the compositions are topically applied for treating or preventing basal cell carcinoma.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: August 6, 2019
    Assignee: PellePharm, Inc.
    Inventors: Marc Barry Brown, Cameron Robert Stevenson, Charles Rodney Greenaway Evans