Abstract: The present invention pertains to humanized anti-Lewis Y antibodies which specifically bind to Lewis Y and do not show any cross-reactivity. Especially, the humanized anti-Lewis Y antibodies do not bind to Lewis b or any other blood group carbohydrate antigen. In particular, the present invention is directed to humanized anti-Lewis Y antibodies which are useful in the treatment of cancer.
Type:
Grant
Filed:
June 29, 2021
Date of Patent:
September 16, 2025
Assignee:
Pentixapharm AG
Inventors:
Antje Danielczyk, Johanna Gellert, Anke Flechner, Patrik Kehler