Patents Assigned to PEPTCELL LIMITED
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Publication number: 20230233660Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: ApplicationFiled: September 9, 2022Publication date: July 27, 2023Applicant: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Patent number: 11439702Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: GrantFiled: September 4, 2020Date of Patent: September 13, 2022Assignee: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Publication number: 20210220453Abstract: The present specification discloses Trypanosoma antigens, immunogenic compositions and medicaments comprising such Trypanosoma antigens, methods and uses for such Trypanosoma antigens and immunogenic compositions for treating a Trypanosoma-based disease.Type: ApplicationFiled: April 3, 2021Publication date: July 22, 2021Applicant: PepTcell LimitedInventors: Olga Pleguezuelos Mateo, Wilson Caparros-Wanderley, Gregory A. Stoloff
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Patent number: 10973897Abstract: The present specification discloses Trypanosoma antigens, immunogenic compositions and medicaments comprising such Trypanosoma antigens, methods and uses for such Trypanosoma antigens and immunogenic compositions for treating a Trypanosoma-based disease.Type: GrantFiled: April 14, 2017Date of Patent: April 13, 2021Assignee: PepTcell LimitedInventors: Olga Pleguezuelos Mateo, Wilson Caparros-Wanderley, Gregory A. Stoloff
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Publication number: 20200397889Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: ApplicationFiled: September 4, 2020Publication date: December 24, 2020Applicant: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Patent number: 10765734Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: GrantFiled: March 7, 2019Date of Patent: September 8, 2020Assignee: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Publication number: 20190365883Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: ApplicationFiled: August 14, 2019Publication date: December 5, 2019Applicant: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Publication number: 20190201519Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: ApplicationFiled: March 7, 2019Publication date: July 4, 2019Applicant: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Patent number: 10335480Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: GrantFiled: January 22, 2018Date of Patent: July 2, 2019Assignee: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Patent number: 10279032Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: GrantFiled: January 8, 2018Date of Patent: May 7, 2019Assignee: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Publication number: 20180185470Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: ApplicationFiled: January 22, 2018Publication date: July 5, 2018Applicant: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Publication number: 20180147277Abstract: The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.Type: ApplicationFiled: January 8, 2018Publication date: May 31, 2018Applicant: PepTcell LimitedInventors: Gregory A. Stoloff, Wilson Romero Caparros-Wanderley
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Patent number: 9944693Abstract: The present specification discloses HIV antigens, immunogenic compositions and medicaments comprising such HIV antigens, methods and uses for such HIV antigens and immunogenic compositions and medicaments for making a ?-HIV antibody, as well as ?-HIV antibodies, therapeutic compositions an medicaments comprising such ?-HIV antibodies, and methods and uses for such ?-HIV antibodies and therapeutic compositions and medicaments for treating an HIV-based disease.Type: GrantFiled: December 8, 2014Date of Patent: April 17, 2018Assignee: PepTcell LimitedInventors: Wilson Caparrós-Wanderley, Gregory A. Stoloff
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Patent number: 9889191Abstract: Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-6, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: SEQ?ID?1 DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ?ID?2 LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ?ID?3 DLIFLARSALILRGSVAHKSC SEQ?ID?4 PGIADIEDLTLLARSMVVVRP SEQ?ID?5 LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ?ID?6 IIGILHLILWILDRLFFKCIYRLF wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.Type: GrantFiled: August 8, 2016Date of Patent: February 13, 2018Assignee: PepTcell LimitedInventors: Gregory Alan Stoloff, Wilson Romero Caparros-Wanderley
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Publication number: 20170296637Abstract: The present specification discloses Trypanosoma antigens, immunogenic compositions and medicaments comprising such Trypanosoma antigens, methods and uses for such Trypanosoma antigens and immunogenic compositions for treating a Trypanosoma-based disease.Type: ApplicationFiled: April 14, 2017Publication date: October 19, 2017Applicant: PepTcell LimitedInventors: Olga Pleguezuelos Mateo, Wilson Caparros-Wanderley, Gregory A. Stoloff
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Publication number: 20170028053Abstract: Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-6, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: SEQ?ID?1 DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ?ID?2 LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ?ID?3 DLIFLARSALILRGSVAHKSC SEQ?ID?4 PGIADIEDLTLLARSMVVVRP SEQ?ID?5 LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ?ID?6 IIGILHLILWILDRLFFKCIYRLF wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.Type: ApplicationFiled: August 8, 2016Publication date: February 2, 2017Applicant: PepTcell LimitedInventors: Gregory Alan Stoloff, Wilson Romero Caparros-Wanderley
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Patent number: 9446116Abstract: Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-6, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: SEQ?ID?1 DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ?ID?2 LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ?ID?3 DLIFLARSALILRGSVAHKSC SEQ?ID?4 PGIADIEDLTLLARSMVVVRP SEQ?ID?5 LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ?ID?6 IIGILHLILWILDRLFFKCIYRLF wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.Type: GrantFiled: May 30, 2013Date of Patent: September 20, 2016Assignee: PepTCell LimitedInventors: Gregory Alan Stoloff, Wilson Romero Caparros-Wanderley
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Publication number: 20150158933Abstract: The present specification discloses HIV antigens, immunogenic compositions and medicaments comprising such HIV antigens, methods and uses for such HIV antigens and immunogenic compositions and medicaments for making a ?-HIV antibody, as well as ?-HIV antibodies, therapeutic compositions an medicaments comprising such ?-HIV antibodies, and methods and uses for such ?-HIV antibodies and therapeutic compositions and medicaments for treating an HIV-based disease.Type: ApplicationFiled: December 8, 2014Publication date: June 11, 2015Applicant: PepTcell LimitedInventors: Wilson Caparrós-Wanderley, Gregory A. Stoloff
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Patent number: 8992934Abstract: The present specification discloses an immunogenic composition comprising polypeptide, wherein each of the polypeptides has no more than 100 amino acids, which polypeptides comprises one or more sequences having at least 60% homology with any of SEQ ID 1-4, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-4 that has the same length as the epitope, wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete HIV virus protein.Type: GrantFiled: June 18, 2012Date of Patent: March 31, 2015Assignee: PepTcell LimitedInventors: Gregory Alan Stoloff, Wilson Romero Caparros-Wanderlay
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Publication number: 20130243804Abstract: Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-6, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: SEQ?ID?1 DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ?ID?2 LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ?ID?3 DLIFLARSALILRGSVAHKSC SEQ?ID?4 PGIADIEDLTLLARSMVVVRP SEQ?ID?5 LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ?ID?6 IIGILHLILWILDRLFFKCIYRLF wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.Type: ApplicationFiled: May 30, 2013Publication date: September 19, 2013Applicant: PEPTCELL LIMITEDInventors: Gregory Alan Stoloff, Wilson Romero Caparros-Wanderley