Abstract: A process for the manufacture of peptide Omiganan in solution phase. Novel intermediates in the process for the manufacture of Omiganan and processes for the manufacture of these intermediates.
Type:
Grant
Filed:
June 17, 2008
Date of Patent:
August 9, 2016
Assignee:
PEPTISYNTHA
Inventors:
Roland Callens, Laurent Jeannin, Georges Blondeel
Abstract: The present invention relates to a process for producing N-alkyl-N-trialkylsilylamides from trialkylsilylhalides and N-alkylamides in the presence of a base and in the absence of a solvent.
Abstract: Described are compounds comprising a peptide moiety linked through a linkage to a short-chain polyethylene glycol moiety, more particularly compounds wherein the peptide moiety comprises a self-assembling peptide sequence, and compositions and hydrogels comprising these compounds. Further, methods for the preparation of the present compounds comprising a peptide moiety linked through a linkage to a short-chain polyethylene glycol moiety are disclosed.
Type:
Application
Filed:
July 29, 2013
Publication date:
October 29, 2015
Applicant:
Peptisyntha SA
Inventors:
Laurent JEANNIN, Wafa MOUSSA, Martin BOUSMANNE