Patents Assigned to Peptone, LTD.
  • Spacio-temporal determination of polypeptide structure
    Patent number: 12609183
    Abstract: Disclosed herein are methods of in silico generation of polypeptide structures using time-based data generated from molecular dynamics simulations. Also disclosed herein are methods of predicting an epitope or binding surface of a polypeptide using in silico methods. Also disclosed herein are compositions containing polypeptide therapeutics designed to bind to a predicted epitope structure of a polypeptide, as well as methods of treating a subject by administering to the subject compositions containing the same.
    Type: Grant
    Filed: March 7, 2024
    Date of Patent: April 21, 2026
    Assignee: Peptone, LTD.
    Inventors: Oliver Dutton, Carlo Fisicaro, Matthew Michael Heberling, Louie Derek Henderson, Istvan Redl, Kamil Tamiola