Patents Assigned to PercuSense, Inc.
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Publication number: 20240057905Abstract: A system to automatically detect at least one physiological state is disclosed. The system includes a single probe for insertion within a subject that has an analyte sensor array for continuous monitoring of at least glucose and a second analyte. The system further includes an electronics module that includes a power supply, a processor, memory and a bi-directional communications module. When the electronics module is coupled with the analyte sensor array the power supply delivers power to the analyte sensor array and the processor. The processor analyzing glucose and the second analyte data to detect a first physiological state from a plurality of physiological states.Type: ApplicationFiled: February 24, 2022Publication date: February 22, 2024Applicant: PercuSense, Inc.Inventors: RAJIV SHAH, BRADLEY C LIANG, ELLEN BOWMAN, KATHERINE WOLFE
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Publication number: 20240041359Abstract: In one embodiment, a sensor assembly is disclosed. The sensor assembly includes a first analyte sensor being formed on a first substrate and a second analyte sensor being formed on a second substrate. Wherein the first analyte sensor is coupled to the second analyte sensor within a coupling area defined by an overlap between the first analyte sensor and the second analyte sensor.Type: ApplicationFiled: August 4, 2023Publication date: February 8, 2024Applicant: PercuSense, Inc.Inventor: KATHERINE WOLFE
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Publication number: 20240023847Abstract: In one embodiment, a sensor is disclosed that includes a first conductive substrate coupled to, and electrically isolated from, a second conductive substrate. The sensor includes a first electrode trace within the first conductive substrate with a plurality of first working electrode openings. The sensor also includes a second electrode trace within the first conductive substrate with a plurality of second working electrode openings. Additionally a first transport material is included that covers the plurality of first working electrode openings and a second transport material that covers the plurality of second working electrode openings. A third transport material covers, and forms a barrier between the first and the second transport material. The sensor additionally includes a counter-reference electrode that is formed on the second conductive substrate.Type: ApplicationFiled: July 22, 2022Publication date: January 25, 2024Applicant: PercuSense, Inc.Inventors: Rajiv Shah, Bradley C. Liang, Katherine Wolfe
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Publication number: 20240008778Abstract: An on-body insertion system is described. The on-body system includes a sensor in a first position being substantially parallel to an insertion surface. Activation of an actuator transitions the sensor to a second position. Wherein the transition imparts movement to the sensor that is substantially parallel to the insertion surface and the second position results in the sensing area being beneath the insertion surface.Type: ApplicationFiled: September 22, 2023Publication date: January 11, 2024Applicant: PercuSense, Inc.Inventors: Katherine Wolfe, Joseph Ferreira, Ellen Messer, Rajiv Shah, Konrad Chan
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Publication number: 20230355147Abstract: In one embodiment, a sensor to measure the presence of an analyte is disclosed. The sensor includes a working conductor with an electrode reactive surface. The sensor further includes a first reactive chemistry that is responsive to a first analyte and is in direct contact with the electrode reactive surface. The first reactive chemistry includes an enzyme, a first transport material, and an entrappable cofactor that includes a cofactor for the enzyme coupled to an anchor molecule. The sensor further includes a second transport material that enables diffusion of the first analyte to the first reactive chemistry.Type: ApplicationFiled: April 18, 2023Publication date: November 9, 2023Applicant: PercuSense, Inc.Inventors: KAITLYNN OLCZAK, MIRELIS SANTOS CANCEL, RAJIV SHAH, BRIAN KANNARD, BRADLEY LIANG, ELIZABETH ESPINOZA
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Patent number: 11806135Abstract: Sensing and infusion devices are described. In one embodiment, a sensing and infusion device may include an implantable segment having a sensor. The sensing and infusion device may also include a catheter, and a sensor channel may be formed in the catheter. The sensor channel may be configured to retain at least a portion of the implantable segment.Type: GrantFiled: August 19, 2021Date of Patent: November 7, 2023Assignee: PercuSense, Inc.Inventors: Rajiv Shah, Ellen Messer, Katherine Wolfe, Shaun Pendo
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Patent number: 11806139Abstract: An on-body insertion system is described. The on-body system includes a sensor in a first position being substantially parallel to an insertion surface. Activation of an actuator transitions the sensor to a second position. Wherein the transition imparts movement to the sensor that is substantially parallel to the insertion surface and the second position results in the sensing area being beneath the insertion surface.Type: GrantFiled: October 30, 2020Date of Patent: November 7, 2023Assignee: PercuSense, Inc.Inventors: Katherine Wolfe, Joseph Ferreira, Ellen Messer, Rajiv Shah, Konrad Chan
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Publication number: 20230119049Abstract: An electrode measuring the presence of an analyte is described as one embodiment. The electrode includes a working conductor with an electrode reactive surface and a first reactive chemistry that is responsive to the analyte. The electrode further includes a first transport material that enables flux of the first analyte to the first reactive chemistry and a second transport material that supplies a reactant to the first reactive chemistry. Wherein the first reactive chemistry does not contact the electrode reactive surface while at least partially shadowing a portion of the electrode reactive surface.Type: ApplicationFiled: December 16, 2022Publication date: April 20, 2023Applicant: PercuSense, Inc.Inventors: RAJIV SHAH, BRADLEY C. LIANG, KATHERINE WOLFE, ELLEN MESSER, SHAUN PENDO
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Publication number: 20230106459Abstract: In one embodiment, an infusion set and sensor assembly delivered within a subject is disclosed. The assembly includes a cannula that is terminated at a cannula opening. The assembly further includes a sharp that is at least partially within the hollow of the cannula. A sensor having a proximal end and a distal end is also included in the assembly. The proximal end of the sensor is held in a fixed location while the distal end is retained with a portion of the cannula. The sensor further includes sensor slack, wherein transitioning the sharp from a first position to a second position simultaneously inserts the cannula and sensor to a desired insertion depth within a subject via a single point of insertion.Type: ApplicationFiled: December 9, 2022Publication date: April 6, 2023Applicant: PercuSense, Inc.Inventors: KATHERINE WOLFE, RAJIV SHAH
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Publication number: 20230075014Abstract: A biosensor assembly that measures multiple physical parameters is disclosed. The biosensor assembly includes a first implantable probe and a first skin contacting electrode. Wherein a first physiological parameter is measured between the first implantable probe and the first skin contactable electrode.Type: ApplicationFiled: November 15, 2022Publication date: March 9, 2023Applicant: PercuSense, Inc.Inventors: RAJIV SHAH, BRADLEY C LIANG, ELLEN MESSER, KATHERINE WOLFE
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Patent number: 11553862Abstract: An electrode measuring the presence of an analyte is described as one embodiment. The electrode includes a working conductor with an electrode reactive surface and a first reactive chemistry that is responsive to the analyte. The electrode further includes a first transport material that enables flux of the first analyte to the first reactive chemistry and a second transport material that supplies a reactant to the first reactive chemistry. Wherein the first reactive chemistry does not contact the electrode reactive surface while at least partially shadowing a portion of the electrode reactive surface.Type: GrantFiled: June 22, 2018Date of Patent: January 17, 2023Assignee: PercuSense, Inc.Inventors: Rajiv Shah, Bradley Liang, Katherine Wolfe, Ellen Messer, Shaun Pendo
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Patent number: 11547812Abstract: In one embodiment, an infusion set and sensor assembly delivered within a subject is disclosed. The assembly includes a cannula that is terminated at a cannula opening. The assembly further includes a sharp that is at least partially within the hollow of the cannula. A sensor having a proximal end and a distal end is also included in the assembly. The proximal end of the sensor is held in a fixed location while the distal end is retained with a portion of the cannula. The sensor further includes sensor slack, wherein transitioning the sharp from a first position to a second position simultaneously inserts the cannula and sensor to a desired insertion depth within a subject via a single point of insertion.Type: GrantFiled: July 23, 2020Date of Patent: January 10, 2023Assignee: PercuSense, Inc.Inventors: Katherine Wolfe, Rajiv Shah
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Patent number: 11529053Abstract: A biosensor assembly that measures multiple physical parameters is disclosed. The biosensor assembly includes a first implantable probe and a first skin contacting electrode. Wherein a first physiological parameter is measured between the first implantable probe and the first skin contactable electrode.Type: GrantFiled: August 3, 2018Date of Patent: December 20, 2022Assignee: PercuSense, Inc.Inventors: Rajiv Shah, Bradley C Liang, Ellen Messer, Katherine Wolfe
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Publication number: 20220248987Abstract: Sensing and infusion devices are described. In one embodiment, a sensing and infusion device may include an implantable segment having a sensor. The sensing and infusion device may also include a catheter, and a sensor channel may be formed in the catheter. The sensor channel may be configured to retain at least a portion of the implantable segment.Type: ApplicationFiled: August 19, 2021Publication date: August 11, 2022Applicant: Percusense, Inc.Inventors: Rajiv SHAH, Ellen MESSER, Katherine WOLFE, Shaun PENDO
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Publication number: 20220183598Abstract: A working electrode measuring the presence of an analyte is described as one embodiment. The working electrode includes a working conductor with a reactive surface that is operated at a first potential. The working electrode further includes a first transport material with properties that enable analyte flux to the reactive surface. Additionally, the working electrode has a second transport material with properties that enable reactant flux to the reactive surface, wherein the analyte flux and the reactant flux are in dissimilar directions.Type: ApplicationFiled: February 28, 2022Publication date: June 16, 2022Applicant: PercuSense, Inc.Inventors: Rajiv Shah, Bradley C. Liang, Katherine Wolfe, Ellen K. Messer, Shaun M. Pendo
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Patent number: 11298059Abstract: A working electrode measuring the presence of an analyte is described as one embodiment. The working electrode includes a working conductor with a reactive surface that is operated at a first potential. The working electrode further includes a first transport material with properties that enable analyte flux to the reactive surface. Additionally, the working electrode has a second transport material with properties that enable reactant flux to the reactive surface, wherein the analyte flux and the reactant flux are in dissimilar directions.Type: GrantFiled: March 28, 2017Date of Patent: April 12, 2022Assignee: PercuSense, Inc.Inventors: Rajiv Shah, Bradley Liang, Katherine Wolfe, Ellen K Messer, Shaun M Pendo
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Patent number: 11284816Abstract: A system to automatically detect at least one physiological state is disclosed. The system includes a single probe for insertion within a subject that has an analyte sensor array for continuous monitoring of at least glucose and a second analyte. The system further includes an electronics module that includes a power supply, a processor, memory and a bi-directional communications module. When the electronics module is coupled with the analyte sensor array the power supply delivers power to the analyte sensor array and the processor. The processor analyzing glucose and the second analyte data to detect a first physiological state from a plurality of physiological states.Type: GrantFiled: February 12, 2019Date of Patent: March 29, 2022Assignee: PercuSense, Inc.Inventors: Rajiv Shah, Bradley C Liang, Ellen Bowman, Katherine Wolfe
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Publication number: 20210267548Abstract: In one embodiment, an integrated cannula and sensor assembly is disclosed. The integrated cannula and sensor assembly includes a cannula with a proximal end and a distal end. The cannula also has a body and a tip. The body includes a channel and a body distal that is defined between the proximal end and the distal end. The tip is defined between the body distal and the distal end. The assembly further includes a sensor assembly that is located within the channel, wherein the tip further includes an undercut configured to retain the sensor assembly.Type: ApplicationFiled: February 26, 2021Publication date: September 2, 2021Applicant: PercuSense, Inc.Inventor: KATHERINE WOLFE
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Publication number: 20210236065Abstract: An apparatus for early detection of sepsis in a host is disclosed. The apparatus includes a first sensor to directly measure a glucose level, a second sensor to directly measure a lactate level and a third sensor to directly measure a tissue oxygen level. The first sensor, the second sensor, and the third sensor all being inserted at a single point of entry in a subcutaneous space of the host such that a predetermined correlation between the glucose level, lactate level, and tissue oxygen level signals conditions related to sepsis.Type: ApplicationFiled: November 21, 2020Publication date: August 5, 2021Applicant: Percusense, Inc.Inventors: RAJIV SHAH, BRADLEY C LIANG, BAHAR SUTORIUS, KATHERINE WOLFE, ELLEN MESSER, SHAUN PENDO
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Publication number: 20210045661Abstract: An on-body insertion system is described. The on-body system includes a sensor in a first position being substantially parallel to an insertion surface. Activation of an actuator transitions the sensor to a second position. Wherein the transition imparts movement to the sensor that is substantially parallel to the insertion surface and the second position results in the sensing area being beneath the insertion surface.Type: ApplicationFiled: October 30, 2020Publication date: February 18, 2021Applicant: PercuSense, Inc.Inventors: Katherine Wolfe, Joseph Ferreira, Ellen Messer, Rajiv Shah, Konrad Chan