Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: A system/method allowing personalized ex vivo customization of a generic ophthalmic lens blank (OLB) or ophthalmic lens with known diopter (OKD) based on localized field-measured patient characteristics is disclosed. The OLB is composed of a clear material that contains an ultraviolet (UV) absorbing compound. The refractive index of a portion of the clear material may be customized by spatial modification (CSM) of its refractive index via the use of pulsed laser radiation (PLR). The customization of clear material (i) creates a lens which cannot be created otherwise, or (ii) eliminates the need for remote laboratory fabrication of a customized intraocular lens (IOL) for the patient. The OLB is retained within a secured lens container (SLC) providing for precise physical orientation of the OLB haptics and OLB lens structure with respect to the application of PLR to the OLB.

Abstract: An ophthalmic laser treatment system and method providing for a liquid optical interface (LOI) with a patient eye surface (PES) using an elliptical ocular suction ring (OSR) is disclosed. A disposable ocular patient interface (OPI) provides for simultaneous differential vacuum mating of the PES, OSR, OPI, and an optical window retainer (OWR). The PES, OSR, OPI, and OWR form an enclosed volume in which liquid may be interjected to cover the PES during laser treatment. A vacuum suction pump (VSP) provides controlled vacuum to the OPI ensuring proper differential vacuum mating (DVM) between the PES, OSR, OPI, and OWR during laser treatment. The OWR connects to a laser objective bracket (LOB) via an ocular force sensor (OFS) and an optical separator bracket (OSB). The OFS senses applied pressure to the PES and provides data to a computerized control device (CCD) that limits applied pressure to the PES during laser treatment.

Abstract: A system/method allowing personalized ex vivo customization of a generic ophthalmic lens blank (OLB) or ophthalmic lens with known diopter (OKD) based on localized field-measured patient characteristics is disclosed. The OLB is composed of an acrylic material that has been infused with an ultraviolet (UV) absorbing compound rendering it amenable to customized spatial modification (CSM) of its refractive index via the use of pulsed laser radiation (PLR). The CSM of refractive index eliminates the need for remote laboratory fabrication of a customized intraocular lens (IOL) for the patient. The OLB is retained within a secured lens container (SLC) providing for precise physical orientation of the OLB haptics and OLB lens structure with respect to the application of PLR to the OLB. The SLC contains a lens filler material (LFM) covering the OLB and is hermetically sealed after the OLB has been positioned within the SLC interior and prior to sterilization of the SLC+OLB combination.

Abstract: An ophthalmic laser treatment system and method providing for a liquid optical interface (LOI) with a patient eye surface (PES) using an elliptical ocular suction ring (OSR) is disclosed. A disposable ocular patient interface (OPI) provides for simultaneous differential vacuum mating of the PES, OSR, OPI, and an optical window retainer (OWR). The PES, OSR, OPI, and OWR form an enclosed volume in which liquid may be interjected to cover the PES during laser treatment. A vacuum suction pump (VSP) provides controlled vacuum to the OPI ensuring proper differential vacuum mating (DVM) between the PES, OSR, OPI, and OWR during laser treatment. The OWR connects to a laser objective bracket (LOB) via an ocular force sensor (OFS) and an optical separator bracket (OSB). The OFS senses applied pressure to the PES and provides data to a computerized control device (CCD) that limits applied pressure to the PES during laser treatment.

Abstract: A system/method allowing personalized ex vivo customization of a generic ophthalmic lens blank (OLB) or ophthalmic lens with known diopter (OKD) based on localized field-measured patient characteristics is disclosed. The OLB is composed of an acrylic material that has been infused with an ultraviolet (UV) absorbing compound rendering it amenable to customized spatial modification (CSM) of its refractive index via the use of pulsed laser radiation (PLR). The CSM of refractive index eliminates the need for remote laboratory fabrication of a customized intraocular lens (IOL) for the patient. The OLB is retained within a secured lens container (SLC) providing for precise physical orientation of the OLB haptics and OLB lens structure with respect to the application of PLR to the OLB. The SLC contains a lens filler material (LFM) covering the OLB and is hermetically sealed after the OLB has been positioned within the SLC interior and prior to sterilization of the SLC+OLB combination.

Abstract: A system/method allowing personalized ex vivo customization of a generic ophthalmic lens blank (OLB) or ophthalmic lens with known diopter (OKD) based on localized field-measured patient characteristics is disclosed. The OLB is composed of a clear material that contains an ultraviolet (UV) absorbing compound. The refractive index of a portion of the clear material may be customized by spatial modification (CSM) of its refractive index via the use of pulsed laser radiation (PLR). The customization of clear material (i) creates a lens which cannot be created otherwise, or (ii) eliminates the need for remote laboratory fabrication of a customized intraocular lens (IOL) for the patient. The OLB is retained within a secured lens container (SLC) providing for precise physical orientation of the OLB haptics and OLB lens structure with respect to the application of PLR to the OLB.

Abstract: An ophthalmic laser treatment system and method providing for a liquid optical interface (LOI) with a patient eye surface (PES) using an elliptical ocular suction ring (OSR) is disclosed. A disposable ocular patient interface (OPI) provides for simultaneous differential vacuum mating of the PES, OSR, OPI, and an optical window retainer (OWR). The PES, OSR, OPI, and OWR form an enclosed volume in which liquid may be interjected to cover the PES during laser treatment. A vacuum suction pump (VSP) provides controlled vacuum to the OPI ensuring proper differential vacuum mating (DVM) between the PES, OSR, OPI, and OWR during laser treatment. The OWR connects to a laser objective bracket (LOB) via an ocular force sensor (OFS) and an optical separator bracket (OSB). The OFS senses applied pressure to the PES and provides data to a computerized control device (CCD) that limits applied pressure to the PES during laser treatment.

Abstract: A lens for placement in a human eye, such as intraocular lens, has at least some of its optical properties formed with a laser. The laser forms modified loci in the lens when the modified loci have a different refractive index than the refractive index of the material before modification. Different patterns of modified loci can provide selected dioptic power, toric adjustment, and/or aspheric adjustment provided. Preferably both the anterior and posterior surfaces of the lens are planar for ease of placement in the human eye.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: A system and method for determining the shape of a cornea of an eye illuminates at least one of the interior surface, the posterior surface, and the interior region of the eye with infrared light of a wavelength that can generate fluorescent light from the portion of the cornea illuminated. The generated fluorescent light is then detected. The step of illuminating can comprise focusing the infrared light in a plurality of different planes substantially perpendicular to the optical axis of the eye. From the detected light it is possible to create a map of at least a portion of the interior surface, at least a portion of the posterior surface, and/or portion of the interior region of the cornea. Clarity of vision can be determined by generating autofluorescence from proteins in the pigment epithelial cells of the retina.

Abstract: A lens for placement in a human eye, such as intraocular lens, has at least some of its optical properties formed with a laser. The laser forms modified loci in the lens when the modified loci have a different refractive index than the refractive index of the material before modification. Different patterns of modified loci can provide selected dioptic power, toric adjustment, and/or aspheric adjustment provided. Preferably both the anterior and posterior surfaces of the lens are planar for ease of placement in the human eye.

Abstract: A lens for placement in a human eye, such as intraocular lens, has at least some of its optical properties formed with a laser. The laser forms modified loci in the lens when the modified loci have a different refractive index than the refractive index of the material before modification. Different patterns of modified loci can provide selected dioptic power, toric adjustment, and/or aspheric adjustment provided. Preferably both the anterior and posterior surfaces of the lens are planar for ease of placement in the human eye.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: A system for determining the shape of a cornea of an eye illuminates at least one of the interior surface, the posterior surface, and the interior region of the eye with infrared light of a wavelength that can generate fluorescent light from the portion of the cornea illuminated. The generated fluorescent light is then detected. A step of illuminating can comprise focusing the infrared light in a plurality of different planes substantially perpendicular to the optical axis of the eye. From the detected light it is possible to create a map of at least a portion of the interior surface, at least a portion of the posterior surface, and/or portion of the interior region of the cornea. Clarity of vision can be determined by generating autofluorescence from proteins in the pigment epithelial cells of the retina.