Patents Assigned to Perfusion Technology, LLC
  • Low intensity directed ultrasound (LODUS) mediated blood brain barrier disruption
    Patent number: 7896821
    Abstract: A method and device selectively and reversibly disrupts the blood-brain barrier (BBB) in a selected volume of the brain without the need for exogenous agents. The method and device employ low intensity directed ultrasound (LODUS) that is safe, reduces the danger of cavitation and thermal tissue damage, and is able to expose small or large regions of the brain to achieve a desired therapeutic or prophylactic effect.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: March 1, 2011
    Assignee: Perfusion Technology, LLC
    Inventors: Paul A. Magnin, Ulrich Herken, Albert S. Kyle