Abstract: In the new on-line preparative method, and in the inventive apparatus, the addition of flow medium during chromatography can be varied in parallel, locally and temporally. It is thus possible to improve sections of a total chromatogram in their separation by choosing for such partial problems the optimum compositions of the flow medium. The separations are basically obtained in two different ways: (1) Circular separations are carried out with the help of centrifugal force using a sequential technical flow medium supply, wherein the separation occurs from the inside to the outside. The separated substances can be returned through recycling to the inside of the layer. (2) Anticircular separations are carried out with the help of capillary force using a circular solvent supply, wherein the substance zones are concentrated and/or further developed from the outside to the inside.

Abstract: A planar centrifugal chromatography device includes a chamber (2), and a rotor (3) arranged therein, driven by a motor (12) and serving as a separating element. The rotor has a supporting plate (15) with an adsorbing medium (4) provided thereon. A collecting device (5) is arranged near the outer edge of the rotor, but within the chamber.The characteristics of the invention include the collecting device (5) and the rotor (3) being mounted on a common shaft (10) and each individual point of a wall of the collecting device (5) being farther away from the axis of rotation (14) than the point of the adsorbing medium (4) which is farthest from the axis of rotation (14), and include the distances of individual points on the wall of the collecting device (5), measured from the axis of rotation (14), varying.